Krishnan K - Search Results

1

New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids.

Pathirathna S, Brimelow BC, Jagodic MM, Krishnan K, Jiang X, Zorumski CF, Mennerick S, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Pathirathna S, et al. Among authors: krishnan k. Pain. 2005 Apr;114(3):429-443. doi: 10.1016/j.pain.2005.01.009. Pain. 2005. PMID: 15777868

2

Comparison of effects of U18666A and enantiomeric U18666A on sterol synthesis and induction of apoptosis.

Cenedella RJ, Sexton PS, Krishnan K, Covey DF. Cenedella RJ, et al. Among authors: krishnan k. Lipids. 2005 Jun;40(6):635-40. doi: 10.1007/s11745-005-1426-9. Lipids. 2005. PMID: 16149744

3

The enantiomer of progesterone acts as a molecular neuroprotectant after traumatic brain injury.

VanLandingham JW, Cutler SM, Virmani S, Hoffman SW, Covey DF, Krishnan K, Hammes SR, Jamnongjit M, Stein DG. VanLandingham JW, et al. Among authors: krishnan k. Neuropharmacology. 2006 Nov;51(6):1078-85. doi: 10.1016/j.neuropharm.2006.07.015. Epub 2006 Aug 22. Neuropharmacology. 2006. PMID: 16926035

4

Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens.

Katona BW, Krishnan K, Cai ZY, Manion BD, Benz A, Taylor A, Evers AS, Zorumski CF, Mennerick S, Covey DF. Katona BW, et al. Among authors: krishnan k. Eur J Med Chem. 2008 Jan;43(1):107-13. doi: 10.1016/j.ejmech.2007.02.017. Epub 2007 Mar 12. Eur J Med Chem. 2008. PMID: 17434649

5

Antagonism of neurosteroid modulation of native gamma-aminobutyric acid receptors by (3alpha,5alpha)-17-phenylandrost-16-en-3-ol.

Kelley SP, Alan JK, O'Buckley TK, Mennerick S, Krishnan K, Covey DF, Leslie Morrow A. Kelley SP, et al. Among authors: krishnan k. Eur J Pharmacol. 2007 Oct 31;572(2-3):94-101. doi: 10.1016/j.ejphar.2007.06.028. Epub 2007 Jun 29. Eur J Pharmacol. 2007. PMID: 17658511 Free PMC article.

6

GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices.

Izumi Y, Murayama K, Tokuda K, Krishnan K, Covey DF, Zorumski CF. Izumi Y, et al. Among authors: krishnan k. Eur J Neurosci. 2007 Oct;26(7):1881-8. doi: 10.1111/j.1460-9568.2007.05809.x. Epub 2007 Sep 20. Eur J Neurosci. 2007. PMID: 17883414

7

Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes.

Scaglione JB, Jastrzebska I, Krishnan K, Li P, Akk G, Manion BD, Benz A, Taylor A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Scaglione JB, et al. Among authors: krishnan k. J Med Chem. 2008 Mar 13;51(5):1309-18. doi: 10.1021/jm701128r. Epub 2008 Feb 15. J Med Chem. 2008. PMID: 18275132

8

Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.

Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS. Gale SE, et al. Among authors: krishnan k. J Biol Chem. 2009 Jan 16;284(3):1755-64. doi: 10.1074/jbc.M807210200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18996837 Free PMC article.

9

Synthesis of 19-Trideuterated ent-Testosterone and the GABA(A) Receptor Potentiators ent-Androsterone and ent-Etiocholanolone.

Komarapuri S, Krishnan K, Covey DF. Komarapuri S, et al. Among authors: krishnan k. J Labelled Comp Radiopharm. 2008 Nov;51(14):430-434. doi: 10.1002/jlcr.1558. J Labelled Comp Radiopharm. 2008. PMID: 19122784 Free PMC article.

10

The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction.

Chisari M, Eisenman LN, Krishnan K, Bandyopadhyaya AK, Wang C, Taylor A, Benz A, Covey DF, Zorumski CF, Mennerick S. Chisari M, et al. Among authors: krishnan k. J Neurophysiol. 2009 Aug;102(2):1254-64. doi: 10.1152/jn.00346.2009. Epub 2009 Jun 24. J Neurophysiol. 2009. PMID: 19553485 Free PMC article.

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