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MLL translocations, histone modifications and leukaemia stem-cell development.
Krivtsov AV, Armstrong SA. Krivtsov AV, et al. Nat Rev Cancer. 2007 Nov;7(11):823-33. doi: 10.1038/nrc2253. Nat Rev Cancer. 2007. PMID: 17957188 Review.
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ. Wang J, et al. Among authors: krivtsov a. EMBO J. 2005 Jan 26;24(2):368-81. doi: 10.1038/sj.emboj.7600521. Epub 2005 Jan 6. EMBO J. 2005. PMID: 15635450 Free PMC article.
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA. Krivtsov AV, et al. Nature. 2006 Aug 17;442(7104):818-22. doi: 10.1038/nature04980. Epub 2006 Jul 16. Nature. 2006. PMID: 16862118
MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment.
Stubbs MC, Kim YM, Krivtsov AV, Wright RD, Feng Z, Agarwal J, Kung AL, Armstrong SA. Stubbs MC, et al. Among authors: krivtsov av. Leukemia. 2008 Jan;22(1):66-77. doi: 10.1038/sj.leu.2404951. Epub 2007 Sep 13. Leukemia. 2008. PMID: 17851551 Free PMC article.
H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Krivtsov AV, Feng Z, Lemieux ME, Faber J, Vempati S, Sinha AU, Xia X, Jesneck J, Bracken AP, Silverman LB, Kutok JL, Kung AL, Armstrong SA. Krivtsov AV, et al. Cancer Cell. 2008 Nov 4;14(5):355-68. doi: 10.1016/j.ccr.2008.10.001. Cancer Cell. 2008. PMID: 18977325 Free PMC article.
HOXA9 is required for survival in human MLL-rearranged acute leukemias.
Faber J, Krivtsov AV, Stubbs MC, Wright R, Davis TN, van den Heuvel-Eibrink M, Zwaan CM, Kung AL, Armstrong SA. Faber J, et al. Among authors: krivtsov av. Blood. 2009 Mar 12;113(11):2375-85. doi: 10.1182/blood-2007-09-113597. Epub 2008 Dec 3. Blood. 2009. PMID: 19056693 Free PMC article.
Gene expression profiling of leukemia stem cells.
Krivtsov AV, Wang Y, Feng Z, Armstrong SA. Krivtsov AV, et al. Methods Mol Biol. 2009;538:231-46. doi: 10.1007/978-1-59745-418-6_11. Methods Mol Biol. 2009. PMID: 19277590 Free PMC article.
Transformation from committed progenitor to leukemia stem cells.
Krivtsov AV, Feng Z, Armstrong SA. Krivtsov AV, et al. Ann N Y Acad Sci. 2009 Sep;1176:144-9. doi: 10.1111/j.1749-6632.2009.04966.x. Ann N Y Acad Sci. 2009. PMID: 19796242
MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.
Juszczynski P, Rodig SJ, Ouyang J, O'Donnell E, Takeyama K, Mlynarski W, Mycko K, Szczepanski T, Gaworczyk A, Krivtsov A, Faber J, Sinha AU, Rabinovich GA, Armstrong SA, Kutok JL, Shipp MA. Juszczynski P, et al. Among authors: krivtsov a. Clin Cancer Res. 2010 Apr 1;16(7):2122-30. doi: 10.1158/1078-0432.CCR-09-2765. Epub 2010 Mar 23. Clin Cancer Res. 2010. PMID: 20332322 Free PMC article.
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. Wang Y, et al. Among authors: krivtsov av. Science. 2010 Mar 26;327(5973):1650-3. doi: 10.1126/science.1186624. Science. 2010. PMID: 20339075 Free PMC article.
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