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Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding.
Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Aceto N. Gkountela S, et al. Among authors: krol i. Cell. 2019 Jan 10;176(1-2):98-112.e14. doi: 10.1016/j.cell.2018.11.046. Cell. 2019. PMID: 30633912 Free PMC article.
Detection of circulating tumour cell clusters in human glioblastoma.
Krol I, Castro-Giner F, Maurer M, Gkountela S, Szczerba BM, Scherrer R, Coleman N, Carreira S, Bachmann F, Anderson S, Engelhardt M, Lane H, Evans TRJ, Plummer R, Kristeleit R, Lopez J, Aceto N. Krol I, et al. Br J Cancer. 2018 Aug;119(4):487-491. doi: 10.1038/s41416-018-0186-7. Epub 2018 Aug 1. Br J Cancer. 2018. PMID: 30065256 Free PMC article. Clinical Trial.
Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer.
Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, Aceto N. Vetter M, et al. Among authors: krol i. Breast Cancer Res. 2018 Nov 20;20(1):141. doi: 10.1186/s13058-018-1067-y. Breast Cancer Res. 2018. PMID: 30458879 Free PMC article.
Neutrophils escort circulating tumour cells to enable cell cycle progression.
Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N. Szczerba BM, et al. Among authors: krol i. Nature. 2019 Feb;566(7745):553-557. doi: 10.1038/s41586-019-0915-y. Epub 2019 Feb 6. Nature. 2019. PMID: 30728496
Detection of clustered circulating tumour cells in early breast cancer.
Krol I, Schwab FD, Carbone R, Ritter M, Picocci S, De Marni ML, Stepien G, Franchi GM, Zanardi A, Rissoglio MD, Covelli A, Guidi G, Scarinci D, Castro-Giner F, Mazzarella L, Doglioni C, Borghi F, Milani P, Kurzeder C, Weber WP, Aceto N. Krol I, et al. Br J Cancer. 2021 Jul;125(1):23-27. doi: 10.1038/s41416-021-01327-8. Epub 2021 Mar 24. Br J Cancer. 2021. PMID: 33762721 Free PMC article.
An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression.
Scheidmann MC, Castro-Giner F, Strittmatter K, Krol I, Paasinen-Sohns A, Scherrer R, Donato C, Gkountela S, Szczerba BM, Diamantopoulou Z, Muenst S, Vlajnic T, Kunz L, Vetter M, Rochlitz C, Taylor V, Giachino C, Schroeder T, Platt RJ, Aceto N. Scheidmann MC, et al. Among authors: krol i. Cancer Res. 2022 Feb 15;82(4):681-694. doi: 10.1158/0008-5472.CAN-21-3908. Cancer Res. 2022. PMID: 34916221 Free PMC article.
The metastatic spread of breast cancer accelerates during sleep.
Diamantopoulou Z, Castro-Giner F, Schwab FD, Foerster C, Saini M, Budinjas S, Strittmatter K, Krol I, Seifert B, Heinzelmann-Schwarz V, Kurzeder C, Rochlitz C, Vetter M, Weber WP, Aceto N. Diamantopoulou Z, et al. Among authors: krol i. Nature. 2022 Jul;607(7917):156-162. doi: 10.1038/s41586-022-04875-y. Epub 2022 Jun 22. Nature. 2022. PMID: 35732738
MyCTC chip: microfluidic-based drug screen with patient-derived tumour cells from liquid biopsies.
Schwab FD, Scheidmann MC, Ozimski LL, Kling A, Armbrecht L, Ryser T, Krol I, Strittmatter K, Nguyen-Sträuli BD, Jacob F, Fedier A, Heinzelmann-Schwarz V, Wicki A, Dittrich PS, Aceto N. Schwab FD, et al. Among authors: krol i. Microsyst Nanoeng. 2022 Dec 20;8:130. doi: 10.1038/s41378-022-00467-y. eCollection 2022. Microsyst Nanoeng. 2022. PMID: 36561926 Free PMC article.
49 results