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Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism)--increased Michaelis is Constant (Km) and loss of stereoselectivity of bufuralol 1'-hydroxylation in poor metabolizers.
Dayer P, Gasser R, Gut J, Kronbach T, Robertz GM, Eichelbaum M, Meyer UA. Dayer P, et al. Among authors: kronbach t. Biochem Biophys Res Commun. 1984 Nov 30;125(1):374-80. doi: 10.1016/s0006-291x(84)80378-2. Biochem Biophys Res Commun. 1984. PMID: 6508804
34 results