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U94, the human herpesvirus 6 homolog of the parvovirus nonstructural gene, is highly conserved among isolates and is expressed at low mRNA levels as a spliced transcript.
Rapp JC, Krug LT, Inoue N, Dambaugh TR, Pellett PE. Rapp JC, et al. Virology. 2000 Mar 15;268(2):504-16. doi: 10.1006/viro.1999.0163. Virology. 2000. PMID: 10704358
Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.
Pozharskaya VP, Weakland LL, Zimring JC, Krug LT, Unger ER, Neisch A, Joshi H, Inoue N, Offermann MK. Pozharskaya VP, et al. J Virol. 2004 Jun;78(12):6621-35. doi: 10.1128/JVI.78.12.6621-6635.2004. J Virol. 2004. PMID: 15163753 Free PMC article.
Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid.
Krug LT, Pozharskaya VP, Yu Y, Inoue N, Offermann MK. Krug LT, et al. J Virol. 2004 Aug;78(15):8359-71. doi: 10.1128/JVI.78.15.8359-8371.2004. J Virol. 2004. PMID: 15254208 Free PMC article.
The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.
Klass CM, Krug LT, Pozharskaya VP, Offermann MK. Klass CM, et al. Blood. 2005 May 15;105(10):4028-34. doi: 10.1182/blood-2004-09-3569. Epub 2005 Feb 1. Blood. 2005. PMID: 15687238 Free PMC article.
A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.
Moser JM, Farrell ML, Krug LT, Upton JW, Speck SH. Moser JM, et al. J Virol. 2006 Feb;80(3):1592-8. doi: 10.1128/JVI.80.3.1592-1598.2006. J Virol. 2006. PMID: 16415035 Free PMC article.
Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection.
Cheng BY, Zhi J, Santana A, Khan S, Salinas E, Forrest JC, Zheng Y, Jaggi S, Leatherwood J, Krug LT. Cheng BY, et al. J Virol. 2012 Apr;86(8):4340-57. doi: 10.1128/JVI.05892-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318145 Free PMC article.
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