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Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine.
Lemaire L, Desroches M, Krupa M, Pizzamiglio L, Scalmani P, Mantegazza M. Lemaire L, et al. Among authors: krupa m. PLoS Comput Biol. 2021 Jul 27;17(7):e1009239. doi: 10.1371/journal.pcbi.1009239. eCollection 2021 Jul. PLoS Comput Biol. 2021. PMID: 34314446 Free PMC article.
Time-coded neurotransmitter release at excitatory and inhibitory synapses.
Rodrigues S, Desroches M, Krupa M, Cortes JM, Sejnowski TJ, Ali AB. Rodrigues S, et al. Among authors: krupa m. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1108-15. doi: 10.1073/pnas.1525591113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858411 Free PMC article.
156 results