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10-formyltetrahydrofolate dehydrogenase requires a 4'-phosphopantetheine prosthetic group for catalysis.
Donato H, Krupenko NI, Tsybovsky Y, Krupenko SA. Donato H, et al. Among authors: krupenko sa, krupenko ni. J Biol Chem. 2007 Nov 23;282(47):34159-66. doi: 10.1074/jbc.M707627200. Epub 2007 Sep 20. J Biol Chem. 2007. PMID: 17884809
Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression.
Oleinik NV, Krupenko NI, Priest DG, Krupenko SA. Oleinik NV, et al. Among authors: krupenko sa, krupenko ni. Biochem J. 2005 Nov 1;391(Pt 3):503-11. doi: 10.1042/BJ20050533. Biochem J. 2005. PMID: 16014005 Free PMC article.
Leucovorin-induced resistance against FDH growth suppressor effects occurs through DHFR up-regulation.
Oleinik NV, Krupenko NI, Reuland SN, Krupenko SA. Oleinik NV, et al. Among authors: krupenko sa, krupenko ni. Biochem Pharmacol. 2006 Jul 14;72(2):256-66. doi: 10.1016/j.bcp.2006.04.005. Epub 2006 Apr 25. Biochem Pharmacol. 2006. PMID: 16712799
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Tsybovsky Y, Donato H, Krupenko NI, Davies C, Krupenko SA. Tsybovsky Y, et al. Among authors: krupenko sa, krupenko ni. Biochemistry. 2007 Mar 20;46(11):2917-29. doi: 10.1021/bi0619573. Epub 2007 Feb 16. Biochemistry. 2007. PMID: 17302434
Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway.
Oleinik NV, Krupenko NI, Krupenko SA. Oleinik NV, et al. Among authors: krupenko sa, krupenko ni. Oncogene. 2007 Nov 8;26(51):7222-30. doi: 10.1038/sj.onc.1210526. Epub 2007 May 21. Oncogene. 2007. PMID: 17525747
10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status.
Ghose S, Oleinik NV, Krupenko NI, Krupenko SA. Ghose S, et al. Among authors: krupenko sa, krupenko ni. Mol Cancer Res. 2009 Jan;7(1):99-107. doi: 10.1158/1541-7786.MCR-08-0309. Mol Cancer Res. 2009. PMID: 19147541 Free PMC article.
Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.
Strickland KC, Hoeferlin LA, Oleinik NV, Krupenko NI, Krupenko SA. Strickland KC, et al. Among authors: krupenko sa, krupenko ni. J Biol Chem. 2010 Jan 15;285(3):1627-33. doi: 10.1074/jbc.M109.080556. Epub 2009 Nov 20. J Biol Chem. 2010. PMID: 19933275 Free PMC article.
ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.
Krupenko NI, Dubard ME, Strickland KC, Moxley KM, Oleinik NV, Krupenko SA. Krupenko NI, et al. Among authors: krupenko sa. J Biol Chem. 2010 Jul 23;285(30):23056-63. doi: 10.1074/jbc.M110.128843. Epub 2010 May 24. J Biol Chem. 2010. PMID: 20498374 Free PMC article.
Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes.
Strickland KC, Holmes RS, Oleinik NV, Krupenko NI, Krupenko SA. Strickland KC, et al. Among authors: krupenko sa, krupenko ni. Chem Biol Interact. 2011 May 30;191(1-3):122-8. doi: 10.1016/j.cbi.2010.12.025. Epub 2011 Jan 6. Chem Biol Interact. 2011. PMID: 21215736 Free PMC article.
Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase.
Strickland KC, Krupenko NI, Dubard ME, Hu CJ, Tsybovsky Y, Krupenko SA. Strickland KC, et al. Among authors: krupenko sa, krupenko ni. Chem Biol Interact. 2011 May 30;191(1-3):129-36. doi: 10.1016/j.cbi.2011.01.008. Epub 2011 Jan 14. Chem Biol Interact. 2011. PMID: 21238436 Free PMC article.
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