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Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node-homing adipose tissue dendritic cells.
Kuan EL, Ivanov S, Bridenbaugh EA, Victora G, Wang W, Childs EW, Platt AM, Jakubzick CV, Mason RJ, Gashev AA, Nussenzweig M, Swartz MA, Dustin ML, Zawieja DC, Randolph GJ. Kuan EL, et al. J Immunol. 2015 Jun 1;194(11):5200-10. doi: 10.4049/jimmunol.1500221. Epub 2015 Apr 27. J Immunol. 2015. PMID: 25917096 Free PMC article.
CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability.
Ivanov S, Scallan JP, Kim KW, Werth K, Johnson MW, Saunders BT, Wang PL, Kuan EL, Straub AC, Ouhachi M, Weinstein EG, Williams JW, Briseño C, Colonna M, Isakson BE, Gautier EL, Förster R, Davis MJ, Zinselmeyer BH, Randolph GJ. Ivanov S, et al. Among authors: kuan el. J Clin Invest. 2016 Apr 1;126(4):1581-91. doi: 10.1172/JCI84518. Epub 2016 Mar 21. J Clin Invest. 2016. PMID: 26999610 Free PMC article.
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.
Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ. Duivenvoorden R, et al. Among authors: kuan el. Nat Commun. 2014;5:3065. doi: 10.1038/ncomms4065. Nat Commun. 2014. PMID: 24445279 Free PMC article.
Genetic deletion of mPGES-1 abolishes PGE2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration.
Monrad SU, Kojima F, Kapoor M, Kuan EL, Sarkar S, Randolph GJ, Crofford LJ. Monrad SU, et al. Among authors: kuan el. Prostaglandins Leukot Essent Fatty Acids. 2011 Mar-Apr;84(3-4):113-21. doi: 10.1016/j.plefa.2010.10.003. Epub 2010 Dec 28. Prostaglandins Leukot Essent Fatty Acids. 2011. PMID: 21190819 Free PMC article.