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826 results

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A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.
Inoue M, Sakuraba Y, Motegi H, Kubota N, Toki H, Matsui J, Toyoda Y, Miwa I, Terauchi Y, Kadowaki T, Shigeyama Y, Kasuga M, Adachi T, Fujimoto N, Matsumoto R, Tsuchihashi K, Kagami T, Inoue A, Kaneda H, Ishijima J, Masuya H, Suzuki T, Wakana S, Gondo Y, Minowa O, Shiroishi T, Noda T. Inoue M, et al. Among authors: kubota n. Hum Mol Genet. 2004 Jun 1;13(11):1147-57. doi: 10.1093/hmg/ddh133. Epub 2004 Apr 21. Hum Mol Genet. 2004. PMID: 15102714
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al. Kubota N, et al. Mol Cell. 1999 Oct;4(4):597-609. doi: 10.1016/s1097-2765(00)80210-5. Mol Cell. 1999. PMID: 10549291 Free article.
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T. Kubota N, et al. Diabetes. 2000 Nov;49(11):1880-9. doi: 10.2337/diabetes.49.11.1880. Diabetes. 2000. PMID: 11078455
The role of PPARgamma as a thrifty gene both in mice and humans.
Hara K, Kubota N, Tobe K, Terauchi Y, Miki H, Komeda K, Tamemoto H, Yamauchi T, Hagura R, Ito C, Akanuma Y, Kadowaki T. Hara K, et al. Among authors: kubota n. Br J Nutr. 2000 Dec;84 Suppl 2:S235-9. doi: 10.1079/096582197388608. Br J Nutr. 2000. PMID: 11242476
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
Yamauchi T, Waki H, Kamon J, Murakami K, Motojima K, Komeda K, Miki H, Kubota N, Terauchi Y, Tsuchida A, Tsuboyama-Kasaoka N, Yamauchi N, Ide T, Hori W, Kato S, Fukayama M, Akanuma Y, Ezaki O, Itai A, Nagai R, Kimura S, Tobe K, Kagechika H, Shudo K, Kadowaki T. Yamauchi T, et al. Among authors: kubota n. J Clin Invest. 2001 Oct;108(7):1001-13. doi: 10.1172/JCI12864. J Clin Invest. 2001. PMID: 11581301 Free PMC article.
826 results