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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development.
Wang X, He Q, Zhou C, Xu Y, Liu D, Fujiwara N, Kubota N, Click A, Henderson P, Vancil J, Marquez CA, Gunasekaran G, Schwartz ME, Tabrizian P, Sarpel U, Fiel MI, Diao Y, Sun B, Hoshida Y, Liang S, Zhong Z. Wang X, et al. Among authors: kubota n. Immunity. 2023 Jan 10;56(1):58-77.e11. doi: 10.1016/j.immuni.2022.11.013. Epub 2022 Dec 14. Immunity. 2023. PMID: 36521495 Free PMC article.
The phosphatidylserine targeting antibody bavituximab plus pembrolizumab in unresectable hepatocellular carcinoma: a phase 2 trial.
Hsiehchen D, Beg MS, Kainthla R, Lohrey J, Kazmi SM, Khosama L, Maxwell MC, Kline H, Katz C, Hassan A, Kubota N, Siglinsky E, Pillai AK, Youssoufian H, Mockbee C, Culm K, Uhlik M, Benjamin L, Brekken RA, Ahn C, Singal AG, Zhu H, Hoshida Y, Yopp AC. Hsiehchen D, et al. Among authors: kubota n. Nat Commun. 2024 Mar 11;15(1):2178. doi: 10.1038/s41467-024-46542-y. Nat Commun. 2024. PMID: 38467639 Free PMC article. Clinical Trial.
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. Wang Z, et al. Among authors: kubota n. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533505. doi: 10.1101/2023.03.20.533505. bioRxiv. 2023. PMID: 36993727 Free PMC article. Updated. Preprint.
Lenvatinib recruits cytotoxic GZMK+CD8 T cells in hepatocellular carcinoma.
Yamada T, Fujiwara N, Kubota N, Matsushita Y, Nakatsuka T, Kurosaki S, Minami T, Tateishi R, Ichida A, Arita J, Hasegawa K, Koike K, Fujishiro M, Nakagawa H. Yamada T, et al. Among authors: kubota n. Hepatol Commun. 2023 Jul 17;7(8):e0209. doi: 10.1097/HC9.0000000000000209. eCollection 2023 Aug 1. Hepatol Commun. 2023. PMID: 37471053 Free PMC article.
826 results