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µ-Calpain conversion of antiapoptotic Bfl-1 (BCL2A1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosis.
Valero JG, Cornut-Thibaut A, Jugé R, Debaud AL, Giménez D, Gillet G, Bonnefoy-Bérard N, Salgado J, Salles G, Aouacheria A, Kucharczak J. Valero JG, et al. Among authors: kucharczak j. PLoS One. 2012;7(6):e38620. doi: 10.1371/journal.pone.0038620. Epub 2012 Jun 20. PLoS One. 2012. PMID: 22745672 Free PMC article.
TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1.
Lionnard L, Duc P, Brennan MS, Kueh AJ, Pal M, Guardia F, Mojsa B, Damiano MA, Mora S, Lassot I, Ravichandran R, Cochet C, Aouacheria A, Potts PR, Herold MJ, Desagher S, Kucharczak J. Lionnard L, et al. Among authors: kucharczak j. Cell Death Differ. 2019 May;26(5):902-917. doi: 10.1038/s41418-018-0169-5. Epub 2018 Jul 24. Cell Death Differ. 2019. PMID: 30042493 Free PMC article.
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