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TIGIT predominantly regulates the immune response via regulatory T cells.
Kurtulus S, Sakuishi K, Ngiow SF, Joller N, Tan DJ, Teng MW, Smyth MJ, Kuchroo VK, Anderson AC. Kurtulus S, et al. Among authors: kuchroo vk. J Clin Invest. 2015 Nov 2;125(11):4053-62. doi: 10.1172/JCI81187. Epub 2015 Sep 28. J Clin Invest. 2015. PMID: 26413872 Free PMC article.
Interplay between effector Th17 and regulatory T cells.
Awasthi A, Murugaiyan G, Kuchroo VK. Awasthi A, et al. Among authors: kuchroo vk. J Clin Immunol. 2008 Nov;28(6):660-70. doi: 10.1007/s10875-008-9239-7. Epub 2008 Sep 23. J Clin Immunol. 2008. PMID: 18810613
TIMs: central regulators of immune responses.
Hafler DA, Kuchroo V. Hafler DA, et al. J Exp Med. 2008 Nov 24;205(12):2699-701. doi: 10.1084/jem.20082429. Epub 2008 Nov 17. J Exp Med. 2008. PMID: 19015312 Free PMC article.
T-bet, a Th1 transcription factor regulates the expression of Tim-3.
Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos-Peyton CA, Glimcher LH, Kuchroo VK. Anderson AC, et al. Among authors: kuchroo vk. Eur J Immunol. 2010 Mar;40(3):859-66. doi: 10.1002/eji.200939842. Eur J Immunol. 2010. PMID: 20049876 Free PMC article.
TIM-3 and its regulatory role in immune responses.
Zhu C, Anderson AC, Kuchroo VK. Zhu C, et al. Among authors: kuchroo vk. Curr Top Microbiol Immunol. 2011;350:1-15. doi: 10.1007/82_2010_84. Curr Top Microbiol Immunol. 2011. PMID: 20700701 Review.
Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.
Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK. Joller N, et al. Among authors: kuchroo vk. J Immunol. 2011 Feb 1;186(3):1338-42. doi: 10.4049/jimmunol.1003081. Epub 2011 Jan 3. J Immunol. 2011. PMID: 21199897 Free PMC article.
Type 1 regulatory T cells (Tr1) in autoimmunity.
Pot C, Apetoh L, Kuchroo VK. Pot C, et al. Among authors: kuchroo vk. Semin Immunol. 2011 Jun;23(3):202-8. doi: 10.1016/j.smim.2011.07.005. Epub 2011 Aug 12. Semin Immunol. 2011. PMID: 21840222 Free PMC article. Review.
427 results