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Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase.
Murillas R, Simms KS, Hatakeyama S, Weissman AM, Kuehn MR. Murillas R, et al. Among authors: kuehn mr. J Biol Chem. 2002 Jan 25;277(4):2897-907. doi: 10.1074/jbc.M110047200. Epub 2001 Nov 20. J Biol Chem. 2002. PMID: 11717310
N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies.
Sharma P, Murillas R, Zhang H, Kuehn MR. Sharma P, et al. Among authors: kuehn mr. J Cell Sci. 2010 Apr 15;123(Pt 8):1227-34. doi: 10.1242/jcs.060160. Epub 2010 Mar 16. J Cell Sci. 2010. PMID: 20233849 Free PMC article.
SENP1-modulated sumoylation regulates retinoblastoma protein (RB) and Lamin A/C interaction and stabilization.
Sharma P, Kuehn MR. Sharma P, et al. Among authors: kuehn mr. Oncogene. 2016 Dec 15;35(50):6429-6438. doi: 10.1038/onc.2016.177. Epub 2016 Jun 6. Oncogene. 2016. PMID: 27270425
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch.
Oberst A, Malatesta M, Aqeilan RI, Rossi M, Salomoni P, Murillas R, Sharma P, Kuehn MR, Oren M, Croce CM, Bernassola F, Melino G. Oberst A, et al. Among authors: kuehn mr. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11280-5. doi: 10.1073/pnas.0701773104. Epub 2007 Jun 25. Proc Natl Acad Sci U S A. 2007. PMID: 17592138 Free PMC article.
Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads.
Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR. Kumar A, et al. Among authors: kuehn mr. J Biol Chem. 2001 Jan 5;276(1):656-61. doi: 10.1074/jbc.M004649200. J Biol Chem. 2001. PMID: 11024047
Genetic dissection of nodal function in patterning the mouse embryo.
Lowe LA, Yamada S, Kuehn MR. Lowe LA, et al. Among authors: kuehn mr. Development. 2001 May;128(10):1831-43. Development. 2001. PMID: 11311163
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.
Zhou X, Sasaki H, Lowe L, Hogan BL, Kuehn MR. Zhou X, et al. Among authors: kuehn mr. Nature. 1993 Feb 11;361(6412):543-7. doi: 10.1038/361543a0. Nature. 1993. PMID: 8429908
Novel testis- and embryo-specific isoforms of the phosphofructokinase-1 muscle type gene.
Yamada S, Nakajima H, Kuehn MR. Yamada S, et al. Among authors: kuehn mr. Biochem Biophys Res Commun. 2004 Apr 2;316(2):580-7. doi: 10.1016/j.bbrc.2004.02.089. Biochem Biophys Res Commun. 2004. PMID: 15020257
Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.
Lowe LA, Supp DM, Sampath K, Yokoyama T, Wright CV, Potter SS, Overbeek P, Kuehn MR. Lowe LA, et al. Among authors: kuehn mr. Nature. 1996 May 9;381(6578):158-61. doi: 10.1038/381158a0. Nature. 1996. PMID: 8610013
Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes.
Dahle Ø, Kumar A, Kuehn MR. Dahle Ø, et al. Among authors: kuehn mr. Sci Signal. 2010 Jun 22;3(127):ra48. doi: 10.1126/scisignal.2000841. Sci Signal. 2010. PMID: 20571128 Free PMC article.
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