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A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ. Mitsukawa K, et al. Among authors: kuhn r. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18712-7. doi: 10.1073/pnas.0508063102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339898 Free PMC article.
Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines.
Marinozzi M, Serpi M, Amori L, Gavilan Diaz M, Costantino G, Meyer U, Flor PJ, Gasparini F, Heckendorn R, Kuhn R, Giorgi G, Hermit MB, Thomsen C, Pellicciari R. Marinozzi M, et al. Among authors: kuhn r. Bioorg Med Chem. 2007 May 1;15(9):3161-70. doi: 10.1016/j.bmc.2007.02.040. Epub 2007 Feb 22. Bioorg Med Chem. 2007. PMID: 17350267
Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7.
Sansig G, Bushell TJ, Clarke VR, Rozov A, Burnashev N, Portet C, Gasparini F, Schmutz M, Klebs K, Shigemoto R, Flor PJ, Kuhn R, Knoepfel T, Schroeder M, Hampson DR, Collett VJ, Zhang C, Duvoisin RM, Collingridge GL, van Der Putten H. Sansig G, et al. Among authors: kuhn r. J Neurosci. 2001 Nov 15;21(22):8734-45. doi: 10.1523/JNEUROSCI.21-22-08734.2001. J Neurosci. 2001. PMID: 11698585 Free PMC article.
1,307 results