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Incorporation of tryptophan analogues into the lantibiotic nisin.
Zhou L, Shao J, Li Q, van Heel AJ, de Vries MP, Broos J, Kuipers OP. Zhou L, et al. Among authors: Kuipers OP. Amino Acids. 2016 May;48(5):1309-18. doi: 10.1007/s00726-016-2186-3. Epub 2016 Feb 12. Amino Acids. 2016. PMID: 26872656 Free PMC article.
Autoregulation of subtilin biosynthesis in Bacillus subtilis: the role of the spa-box in subtilin-responsive promoters.
Kleerebezem M, Bongers R, Rutten G, de Vos WM, Kuipers OP. Kleerebezem M, et al. Among authors: Kuipers OP. Peptides. 2004 Sep;25(9):1415-24. doi: 10.1016/j.peptides.2003.11.025. Peptides. 2004. PMID: 15374645
The production of the type I antimicrobial peptide (AMP) subtilin by Bacillus subtilis is regulated in a cell-density-dependent manner [Kleerebezem M, de Vos WM, Kuipers OP. ...
The production of the type I antimicrobial peptide (AMP) subtilin by Bacillus subtilis is regulated in a cell-density-dependent manner [Klee …
Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence.
Majchrzykiewicz JA, Lubelski J, Moll GN, Kuipers A, Bijlsma JJ, Kuipers OP, Rink R. Majchrzykiewicz JA, et al. Among authors: Kuipers A, Kuipers OP. Antimicrob Agents Chemother. 2010 Apr;54(4):1498-505. doi: 10.1128/AAC.00883-09. Epub 2010 Jan 25. Antimicrob Agents Chemother. 2010. PMID: 20100873 Free PMC article.
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation.
Rink R, Wierenga J, Kuipers A, Kluskens LD, Driessen AJ, Kuipers OP, Moll GN. Rink R, et al. Among authors: Kuipers A, Kuipers OP. Appl Environ Microbiol. 2007 Sep;73(18):5809-16. doi: 10.1128/AEM.01104-07. Epub 2007 Jul 27. Appl Environ Microbiol. 2007. PMID: 17660303 Free PMC article.
NisC binds the FxLx motif of the nisin leader peptide.
Abts A, Montalban-Lopez M, Kuipers OP, Smits SH, Schmitt L. Abts A, et al. Among authors: Kuipers OP. Biochemistry. 2013 Aug 13;52(32):5387-95. doi: 10.1021/bi4008116. Epub 2013 Aug 2. Biochemistry. 2013. PMID: 23869662
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