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Biosynthesis of drug glucuronides for use as authentic standards.
Soars MG, Mattiuz EL, Jackson DA, Kulanthaivel P, Ehlhardt WJ, Wrighton SA. Soars MG, et al. Among authors: kulanthaivel p. J Pharmacol Toxicol Methods. 2002 May-Jun;47(3):161-8. doi: 10.1016/S1056-8719(02)00231-9. J Pharmacol Toxicol Methods. 2002. PMID: 12628307
Application of biocatalysis to drug metabolism: preparation of mammalian metabolites of a biaryl-bis-sulfonamide AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor potentiator using Actinoplanes missouriensis.
Zmijewski M, Gillespie TA, Jackson DA, Schmidt DF, Yi P, Kulanthaivel P. Zmijewski M, et al. Among authors: kulanthaivel p. Drug Metab Dispos. 2006 Jun;34(6):925-31. doi: 10.1124/dmd.106.009522. Epub 2006 Feb 28. Drug Metab Dispos. 2006. PMID: 16507647
In vivo metabolism of [14C]ruboxistaurin in dogs, mice, and rats following oral administration and the structure determination of its metabolites by liquid chromatography/mass spectrometry and NMR spectroscopy.
Barbuch RJ, Campanale K, Hadden CE, Zmijewski M, Yi P, O'Bannon DD, Burkey JL, Kulanthaivel P. Barbuch RJ, et al. Among authors: kulanthaivel p. Drug Metab Dispos. 2006 Feb;34(2):213-24. doi: 10.1124/dmd.105.007401. Epub 2005 Oct 28. Drug Metab Dispos. 2006. PMID: 16258078
Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I.
Kulanthaivel P, Kreuzman AJ, Strege MA, Belvo MD, Smitka TA, Clemens M, Swartling JR, Minton KL, Zheng F, Angleton EL, Mullen D, Jungheim LN, Klimkowski VJ, Nicas TI, Thompson RC, Peng SB. Kulanthaivel P, et al. J Biol Chem. 2004 Aug 27;279(35):36250-8. doi: 10.1074/jbc.M405884200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173160
Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure.
Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, Kulanthaivel P, Jackson KA, Chow KH, McCann DJ, Hu H, Anderson S, Furr NA, Barbuch RJ, Cassidy KC. Zamek-Gliszczynski MJ, et al. Among authors: kulanthaivel p. Drug Metab Dispos. 2013 Apr;41(4):714-26. doi: 10.1124/dmd.112.048488. Epub 2013 Jan 10. Drug Metab Dispos. 2013. PMID: 23305709 Clinical Trial.
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