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41 results

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Page 1
A non-canonical scaffold-type E3 ligase complex mediates protein UFMylation.
Peter JJ, Magnussen HM, DaRosa PA, Millrine D, Matthews SP, Lamoliatte F, Sundaramoorthy R, Kopito RR, Kulathu Y. Peter JJ, et al. Among authors: kulathu y. EMBO J. 2022 Nov 2;41(21):e111015. doi: 10.15252/embj.2022111015. Epub 2022 Sep 19. EMBO J. 2022. PMID: 36121123 Free PMC article.
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wąchalska M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW, Becker T, Beckmann R, Kopito RR. DaRosa PA, et al. Among authors: kulathu y. Nature. 2024 Mar;627(8003):445-452. doi: 10.1038/s41586-024-07073-0. Epub 2024 Feb 21. Nature. 2024. PMID: 38383785 Free PMC article.
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Makhlouf L, Peter JJ, Magnussen HM, Thakur R, Millrine D, Minshull TC, Harrison G, Varghese J, Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN, Zeqiraj E, Kulathu Y. Makhlouf L, et al. Among authors: kulathu y. Nature. 2024 Mar;627(8003):437-444. doi: 10.1038/s41586-024-07093-w. Epub 2024 Feb 21. Nature. 2024. PMID: 38383789 Free PMC article.
VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Lange SM, McFarland MR, Lamoliatte F, Carroll T, Krshnan L, Pérez-Ràfols A, Kwasna D, Shen L, Wallace I, Cole I, Armstrong LA, Knebel A, Johnson C, De Cesare V, Kulathu Y. Lange SM, et al. Among authors: kulathu y. Nat Struct Mol Biol. 2024 Dec;31(12):1872-1887. doi: 10.1038/s41594-024-01354-y. Epub 2024 Jul 8. Nat Struct Mol Biol. 2024. PMID: 38977901
Linking K29-Ub chains to biology.
Lange SM, Kulathu Y. Lange SM, et al. Among authors: kulathu y. Nat Chem Biol. 2021 Aug;17(8):843-844. doi: 10.1038/s41589-021-00833-3. Nat Chem Biol. 2021. PMID: 34239126 No abstract available.
Chemical biology tools to study Deubiquitinases and Ubl proteases.
Gorka M, Magnussen HM, Kulathu Y. Gorka M, et al. Among authors: kulathu y. Semin Cell Dev Biol. 2022 Dec;132:86-96. doi: 10.1016/j.semcdb.2022.02.006. Epub 2022 Feb 22. Semin Cell Dev Biol. 2022. PMID: 35216867 Free article. Review.
41 results