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Modulation of glucose homeostasis by doxepin.
Gupta B, Shakarwal MK, Kumar A, Jaju BP. Gupta B, et al. Methods Find Exp Clin Pharmacol. 1992 Jan-Feb;14(1):61-71. Methods Find Exp Clin Pharmacol. 1992. PMID: 1619970
A single dose of doxepin produced significant hypoglycemia which peaked at 4 h and lasted up to 10 h. On chronic doxepin feeding there was complete attenuation of initial hypoglycemia on the 7th and 14th days, culminating into frank hyperglycemia on the 21st day. ...Simila
A single dose of doxepin produced significant hypoglycemia which peaked at 4 h and lasted up to 10 h. On chronic doxepin feeding ther
Evaluation of analgesic, antipyretic and anti-inflammatory activity of spirobarbitunylphenothiazines in rodents.
Sharma S, Lata S, Kumar A, Srivastava VK. Sharma S, et al. Indian J Physiol Pharmacol. 2002 Apr;46(2):235-40. Indian J Physiol Pharmacol. 2002. PMID: 12500500
The peripheral analgesic activity of test drugs A and B was investigated by acetic acid induced writhing test in Swiss mice while the central analgesic action was assessed by hot-wire (tail flick test) of the analgesiometer and tail-clip test in Wistar rats. ...Analgesic a …
The peripheral analgesic activity of test drugs A and B was investigated by acetic acid induced writhing test in Swiss mice while the …
Effect of amitriptyline on blood glucose level in rabbits.
Gupta B, Shakarwal MK, Kumar A, Jaju BP. Gupta B, et al. Indian J Physiol Pharmacol. 1995 Jul;39(3):279-82. Indian J Physiol Pharmacol. 1995. PMID: 8550126
All the doses of Amitriptyline produced significant hyperglycemia at 4 h, which attained a peak at 24 h with 16 mg/kg dose and appears to be due to blockade of the uptake of monominergic transmitters across the axoplasmic membrane, It (16 mg/kg) also produced glucose intol …
All the doses of Amitriptyline produced significant hyperglycemia at 4 h, which attained a peak at 24 h with 16 mg/kg dose and appear …
Effect of mianserin on blood glucose level in rabbits.
Gupta B, Shakarwal MK, Kumar A, Jaju BP. Gupta B, et al. Indian J Physiol Pharmacol. 1993 Apr;37(2):155-7. Indian J Physiol Pharmacol. 1993. PMID: 8225548
Mianserin (6.0 mg/kg) produced a gradually increasing hyperglycemic effect which became significant (P < 0.01) at 10 h and onwards. ...

Mianserin (6.0 mg/kg) produced a gradually increasing hyperglycemic effect which became significant (P < 0.01) at 10 h and onwards

Modification of glybenclamide hypoglycaemia by verapamil in rabbits.
Saxena KK, Lata S, Saxena RS, Kumar A, Srivastava VK. Saxena KK, et al. Indian J Physiol Pharmacol. 1990 Oct;34(4):277-8. Indian J Physiol Pharmacol. 1990. PMID: 2129228
Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity.
Kumar P, Padi SS, Naidu PS, Kumar A. Kumar P, et al. Methods Find Exp Clin Pharmacol. 2007 Jan-Feb;29(1):19-25. doi: 10.1358/mf.2007.29.1.1063492. Methods Find Exp Clin Pharmacol. 2007. PMID: 17344940
3-Nitropropionic acid (3-NP) is a well known fungic toxin causing neurotoxicity. Systemic administration of 3-NP causes motor and cognitive deficits that are associated with excessive free radical generation. ...Curcumin, a potent antioxidant of dietary polyphenol, …
3-Nitropropionic acid (3-NP) is a well known fungic toxin causing neurotoxicity. Systemic administration of 3-NP causes motor and cog …
Metallothionein induced by cadmium or zinc inhibits lipid peroxidation in rats exposed to dimethylnitrosamine.
Rana SV, Kumar A. Rana SV, et al. Arh Hig Rada Toksikol. 2000 Sep;51(3):279-86. Arh Hig Rada Toksikol. 2000. PMID: 11148932
Dimethylnitrosamine (N-nitrosodimethyamine) is a potent inducer of microsomal lipid peroxidation in the liver and kidneys. The results of this study show that prior exposure of adult rats to cadmium or zinc antagonises the effect of dimethylnitrosamine on lipid peroxidatio …
Dimethylnitrosamine (N-nitrosodimethyamine) is a potent inducer of microsomal lipid peroxidation in the liver and kidneys. The result …
Modulatory influence of Adhatoda vasica Nees leaf extract against gamma irradiation in Swiss albino mice.
Kumar A, Ram J, Samarth RM, Kumar M. Kumar A, et al. Phytomedicine. 2005 Apr;12(4):285-93. doi: 10.1016/j.phymed.2003.12.006. Phytomedicine. 2005. PMID: 15898706
Conversely, animals pre-treated with A. vasica leaf extract showed 81.25% survival till 30 days after exposure and a gradual recovery was noted in the hematological values. ...However, A. vasica leaf extract pretreated irradiated animals exhibited a si …
Conversely, animals pre-treated with A. vasica leaf extract showed 81.25% survival till 30 days after exposure and a gradual r …
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