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Signaling by integrin receptors.
Kumar CC. Kumar CC. Oncogene. 1998 Sep 17;17(11 Reviews):1365-73. doi: 10.1038/sj.onc.1202172. Oncogene. 1998. PMID: 9779984 Review.
Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor.
Samatar AA, Wang L, Mirza A, Koseoglu S, Liu S, Kumar CC. Samatar AA, et al. Among authors: kumar cc. J Biol Chem. 2002 Aug 2;277(31):28118-26. doi: 10.1074/jbc.M203686200. Epub 2002 May 14. J Biol Chem. 2002. PMID: 12011061 Free article.
AKT crystal structure and AKT-specific inhibitors.
Kumar CC, Madison V. Kumar CC, et al. Oncogene. 2005 Nov 14;24(50):7493-501. doi: 10.1038/sj.onc.1209087. Oncogene. 2005. PMID: 16288296 Free article. Review.
AKT1, AKT2 and AKT3-dependent cell survival is cell line-specific and knockdown of all three isoforms selectively induces apoptosis in 20 human tumor cell lines.
Koseoglu S, Lu Z, Kumar C, Kirschmeier P, Zou J. Koseoglu S, et al. Cancer Biol Ther. 2007 May;6(5):755-62. doi: 10.4161/cbt.6.5.3995. Epub 2007 Feb 9. Cancer Biol Ther. 2007. PMID: 17426444
Development of a fluorescence polarization bead-based coupled assay to target different activity/conformation states of a protein kinase.
Lu Z, Yin Z, James L, Syto R, Stafford JM, Koseoglu S, Mayhood T, Myers J, Windsor W, Kirschmeier P, Samatar AA, Malcolm B, Turek-Etienne TC, Kumar CC. Lu Z, et al. Among authors: kumar cc. J Biomol Screen. 2004 Jun;9(4):309-21. doi: 10.1177/1087057104263506. J Biomol Screen. 2004. PMID: 15191648
Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis.
Kumar CC. Kumar CC. Curr Drug Targets. 2003 Feb;4(2):123-31. doi: 10.2174/1389450033346830. Curr Drug Targets. 2003. PMID: 12558065 Review.
Adenoviral-mediated expression of a kinase-dead mutant of Akt induces apoptosis selectively in tumor cells and suppresses tumor growth in mice.
Jetzt A, Howe JA, Horn MT, Maxwell E, Yin Z, Johnson D, Kumar CC. Jetzt A, et al. Among authors: kumar cc. Cancer Res. 2003 Oct 15;63(20):6697-706. Cancer Res. 2003. PMID: 14583464 Free article.
Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein.
Comer KA, Dennis PA, Armstrong L, Catino JJ, Kastan MB, Kumar CC. Comer KA, et al. Among authors: kumar cc. Oncogene. 1998 Mar 12;16(10):1299-308. doi: 10.1038/sj.onc.1201645. Oncogene. 1998. PMID: 9546431
Activation of smooth muscle alpha-actin promoter in ras-transformed cells by treatments with antimitotic agents: correlation with stimulation of SRF:SRE mediated gene transcription.
Kumar CC, Kim JH, Bushel P, Armstrong L, Catino JJ. Kumar CC, et al. J Biochem. 1995 Dec;118(6):1285-92. doi: 10.1093/oxfordjournals.jbchem.a125020. J Biochem. 1995. PMID: 8720148
Suppression of Ras transformation by serum response factor.
Kim JH, Johansen FE, Robertson N, Catino JJ, Prywes R, Kumar CC. Kim JH, et al. Among authors: kumar cc. J Biol Chem. 1994 May 13;269(19):13740-3. J Biol Chem. 1994. PMID: 8188648
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