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Role of genomics-based strategies in overcoming chemotherapeutic resistance.
Kumar MV, Shirley R, Ma Y, Lewis RW. Kumar MV, et al. Curr Pharm Biotechnol. 2004 Oct;5(5):471-80. doi: 10.2174/1389201043376698. Curr Pharm Biotechnol. 2004. PMID: 15544495 Review.
Mitofusin 1 degradation is induced by a disruptor of mitochondrial calcium homeostasis, CGP37157: a role in apoptosis in prostate cancer cells.
Choudhary V, Kaddour-Djebbar I, Alaisami R, Kumar MV, Bollag WB. Choudhary V, et al. Among authors: kumar mv. Int J Oncol. 2014 May;44(5):1767-73. doi: 10.3892/ijo.2014.2343. Epub 2014 Mar 13. Int J Oncol. 2014. PMID: 24626641
Novel role of androgens in mitochondrial fission and apoptosis.
Choudhary V, Kaddour-Djebbar I, Lakshmikanthan V, Ghazaly T, Thangjam GS, Sreekumar A, Lewis RW, Mills IG, Bollag WB, Kumar MV. Choudhary V, et al. Among authors: kumar mv. Mol Cancer Res. 2011 Aug;9(8):1067-77. doi: 10.1158/1541-7786.MCR-10-0445. Epub 2011 Jul 1. Mol Cancer Res. 2011. PMID: 21724752 Free PMC article.
Inhibition of PKCĪ“ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.
Pabla N, Dong G, Jiang M, Huang S, Kumar MV, Messing RO, Dong Z. Pabla N, et al. Among authors: kumar mv. J Clin Invest. 2011 Jul;121(7):2709-22. doi: 10.1172/JCI45586. J Clin Invest. 2011. PMID: 21633170 Free PMC article.
Specific mitochondrial calcium overload induces mitochondrial fission in prostate cancer cells.
Kaddour-Djebbar I, Choudhary V, Brooks C, Ghazaly T, Lakshmikanthan V, Dong Z, Kumar MV. Kaddour-Djebbar I, et al. Among authors: kumar mv. Int J Oncol. 2010 Jun;36(6):1437-44. doi: 10.3892/ijo_00000629. Int J Oncol. 2010. PMID: 20428767
Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents.
Dong G, Wang L, Wang CY, Yang T, Kumar MV, Dong Z. Dong G, et al. Among authors: kumar mv. J Pharmacol Exp Ther. 2008 Jun;325(3):978-84. doi: 10.1124/jpet.108.137398. Epub 2008 Feb 29. J Pharmacol Exp Ther. 2008. PMID: 18310471
Therapeutic advantage of combining calcium channel blockers and TRAIL in prostate cancer.
Kaddour-Djebbar I, Lakshmikanthan V, Shirley RB, Ma Y, Lewis RW, Kumar MV. Kaddour-Djebbar I, et al. Among authors: kumar mv. Mol Cancer Ther. 2006 Aug;5(8):1958-66. doi: 10.1158/1535-7163.MCT-06-0011. Mol Cancer Ther. 2006. PMID: 16928816
SAHA-sensitized prostate cancer cells to TNFalpha-related apoptosis-inducing ligand (TRAIL): mechanisms leading to synergistic apoptosis.
Lakshmikanthan V, Kaddour-Djebbar I, Lewis RW, Kumar MV. Lakshmikanthan V, et al. Among authors: kumar mv. Int J Cancer. 2006 Jul 1;119(1):221-8. doi: 10.1002/ijc.21824. Int J Cancer. 2006. PMID: 16450389
Sensitization of TRAIL-resistant cells by inhibition of heat shock protein 90 with low-dose geldanamycin.
Ma Y, Lakshmikanthan V, Lewis RW, Kumar MV. Ma Y, et al. Among authors: kumar mv. Mol Cancer Ther. 2006 Jan;5(1):170-8. doi: 10.1158/1535-7163.MCT-05-0129. Mol Cancer Ther. 2006. PMID: 16432176
Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells.
Shirley RB, Kaddour-Djebbar I, Patel DM, Lakshmikanthan V, Lewis RW, Kumar MV. Shirley RB, et al. Among authors: kumar mv. Neoplasia. 2005 Dec;7(12):1104-11. doi: 10.1593/neo.05520. Neoplasia. 2005. PMID: 16354593 Free PMC article.
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