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41 results
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High-resolution genetic mapping of putative causal interactions between regions of open chromatin.
Kumasaka N, Knights AJ, Gaffney DJ. Kumasaka N, et al. Nat Genet. 2019 Jan;51(1):128-137. doi: 10.1038/s41588-018-0278-6. Epub 2018 Nov 26. Nat Genet. 2019. PMID: 30478436 Free PMC article.
Influence of adaptive mutations, from thermal adaptation experiments, on the infection cycle of RNA bacteriophage Qβ.
Kashiwagi A, Kadoya T, Kumasaka N, Kumagai T, Tsushima FS, Yomo T. Kashiwagi A, et al. Among authors: kumasaka n. Arch Virol. 2018 Oct;163(10):2655-2662. doi: 10.1007/s00705-018-3895-6. Epub 2018 Jun 4. Arch Virol. 2018. PMID: 29869034
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F, Teufel A, Laudes M, Lieb W, Jacobs G, Beuers U, Weersma RK, Wijmenga C, Marschall HU, Milkiewicz P, Pares A, Kontula K, Chazouillères O, Invernizzi P, Goode E, Spiess K, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, Floreani A, Gulamhusein AF, Eaton JE, Schreiber S, Coltescu C, Bowlus CL, Luketic VA, Odin JA, Chopra KB, Kowdley KV, Chalasani N, Manns MP, Srivastava B, Mells G, Sandford RN, Alexander G, Gaffney DJ, Chapman RW, Hirschfield GM, de Andrade M; UK-PSC Consortium; International IBD Genetics Consortium; International PSC Study Group, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, Anderson CA. Ji SG, et al. Among authors: kumasaka n. Nat Genet. 2017 Feb;49(2):269-273. doi: 10.1038/ng.3745. Epub 2016 Dec 19. Nat Genet. 2017. PMID: 27992413 Free PMC article.
Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells.
Rouhani FJ, Nik-Zainal S, Wuster A, Li Y, Conte N, Koike-Yusa H, Kumasaka N, Vallier L, Yusa K, Bradley A. Rouhani FJ, et al. Among authors: kumasaka n. PLoS Genet. 2016 Apr 7;12(4):e1005932. doi: 10.1371/journal.pgen.1005932. eCollection 2016 Apr. PLoS Genet. 2016. PMID: 27054363 Free PMC article.
Corrigendum: Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.
Kumasaka N, Knights AJ, Gaffney DJ. Kumasaka N, et al. Nat Genet. 2016 Apr;48(4):473. doi: 10.1038/ng0329-473e. Nat Genet. 2016. PMID: 27023776 No abstract available.
Fine-mapping cellular QTLs with RASQUAL and ATAC-seq.
Kumasaka N, Knights AJ, Gaffney DJ. Kumasaka N, et al. Nat Genet. 2016 Feb;48(2):206-13. doi: 10.1038/ng.3467. Epub 2015 Dec 14. Nat Genet. 2016. PMID: 26656845 Free PMC article.
Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen.
Pham TA, Clare S, Goulding D, Arasteh JM, Stares MD, Browne HP, Keane JA, Page AJ, Kumasaka N, Kane L, Mottram L, Harcourt K, Hale C, Arends MJ, Gaffney DJ; Sanger Mouse Genetics Project, Dougan G, Lawley TD. Pham TA, et al. Among authors: kumasaka n. Cell Host Microbe. 2014 Oct 8;16(4):504-16. doi: 10.1016/j.chom.2014.08.017. Epub 2014 Sep 25. Cell Host Microbe. 2014. PMID: 25263220 Free PMC article.
Trans-ethnic meta-analysis of white blood cell phenotypes.
Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, Qayyum R, Yanek LR, Becker DM, Becker LC, Kooperberg C, Keating B, Reis J, Tang H, Boerwinkle E, Kamatani Y, Matsuda K, Kamatani N, Nakamura Y, Kubo M, Liu S, Dehghan A, Felix JF, Hofman A, Uitterlinden AG, van Duijn CM, Franco OH, Longo DL, Singleton AB, Psaty BM, Evans MK, Cupples LA, Rotter JI, O'Donnell CJ, Takahashi A, Wilson JG, Ganesh SK, Nalls MA; CHARGE Hematology; COGENT; BioBank Japan Project (RIKEN) Working Groups. Keller MF, et al. Hum Mol Genet. 2014 Dec 20;23(25):6944-60. doi: 10.1093/hmg/ddu401. Epub 2014 Aug 5. Hum Mol Genet. 2014. PMID: 25096241 Free PMC article.
Genetic background drives transcriptional variation in human induced pluripotent stem cells.
Rouhani F, Kumasaka N, de Brito MC, Bradley A, Vallier L, Gaffney D. Rouhani F, et al. Among authors: kumasaka n. PLoS Genet. 2014 Jun 5;10(6):e1004432. doi: 10.1371/journal.pgen.1004432. eCollection 2014 Jun. PLoS Genet. 2014. PMID: 24901476 Free PMC article.
A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, Morizono T, Hosono N, Kawaguchi T, Takazoe M, Yamada T, Suzuki Y, Tanaka H, Motoya S, Hosokawa M, Arimura Y, Shinomura Y, Matsui T, Matsumoto T, Iida M, Tsunoda T, Nakamura Y, Kamatani N, Kubo M. Yamazaki K, et al. Among authors: kumasaka n. Gastroenterology. 2013 Apr;144(4):781-8. doi: 10.1053/j.gastro.2012.12.021. Epub 2012 Dec 22. Gastroenterology. 2013. PMID: 23266558
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