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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA. Matthews AG, et al. Among authors: kuo aj. Nature. 2007 Dec 13;450(7172):1106-10. doi: 10.1038/nature06431. Epub 2007 Nov 21. Nature. 2007. PMID: 18033247 Free PMC article.
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.
Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D. Koh AS, et al. Among authors: kuo aj. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15878-83. doi: 10.1073/pnas.0808470105. Epub 2008 Oct 7. Proc Natl Acad Sci U S A. 2008. PMID: 18840680 Free PMC article.
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling.
Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, Utz PJ, Shi X, Prinjha RK, Lee K, Garcia BA, Bedford MT, Tarakhovsky A, Cheng X, Gozani O. Levy D, et al. Among authors: kuo ay, kuo aj. Nat Immunol. 2011 Jan;12(1):29-36. doi: 10.1038/ni.1968. Epub 2010 Dec 5. Nat Immunol. 2011. PMID: 21131967 Free PMC article.
75 results