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Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.
Kuperstein I, Broersen K, Benilova I, Rozenski J, Jonckheere W, Debulpaep M, Vandersteen A, Segers-Nolten I, Van Der Werf K, Subramaniam V, Braeken D, Callewaert G, Bartic C, D'Hooge R, Martins IC, Rousseau F, Schymkowitz J, De Strooper B. Kuperstein I, et al. EMBO J. 2010 Oct 6;29(19):3408-20. doi: 10.1038/emboj.2010.211. Epub 2010 Sep 3. EMBO J. 2010. PMID: 20818335 Free PMC article.
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.
Heirendt L, Arreckx S, Pfau T, Mendoza SN, Richelle A, Heinken A, Haraldsdóttir HS, Wachowiak J, Keating SM, Vlasov V, Magnusdóttir S, Ng CY, Preciat G, Žagare A, Chan SHJ, Aurich MK, Clancy CM, Modamio J, Sauls JT, Noronha A, Bordbar A, Cousins B, El Assal DC, Valcarcel LV, Apaolaza I, Ghaderi S, Ahookhosh M, Ben Guebila M, Kostromins A, Sompairac N, Le HM, Ma D, Sun Y, Wang L, Yurkovich JT, Oliveira MAP, Vuong PT, El Assal LP, Kuperstein I, Zinovyev A, Hinton HS, Bryant WA, Aragón Artacho FJ, Planes FJ, Stalidzans E, Maass A, Vempala S, Hucka M, Saunders MA, Maranas CD, Lewis NE, Sauter T, Palsson BØ, Thiele I, Fleming RMT. Heirendt L, et al. Among authors: kuperstein i. Nat Protoc. 2019 Mar;14(3):639-702. doi: 10.1038/s41596-018-0098-2. Nat Protoc. 2019. PMID: 30787451 Free PMC article.
Signalling maps in cancer research: construction and data analysis.
Kondratova M, Sompairac N, Barillot E, Zinovyev A, Kuperstein I. Kondratova M, et al. Among authors: kuperstein i. Database (Oxford). 2018 Jan 1;2018:bay036. doi: 10.1093/database/bay036. Database (Oxford). 2018. PMID: 29688383 Free PMC article.
Community-driven roadmap for integrated disease maps.
Ostaszewski M, Gebel S, Kuperstein I, Mazein A, Zinovyev A, Dogrusoz U, Hasenauer J, Fleming RMT, Le Novère N, Gawron P, Ligon T, Niarakis A, Nickerson D, Weindl D, Balling R, Barillot E, Auffray C, Schneider R. Ostaszewski M, et al. Among authors: kuperstein i. Brief Bioinform. 2019 Mar 25;20(2):659-670. doi: 10.1093/bib/bby024. Brief Bioinform. 2019. PMID: 29688273 Free PMC article. Review.
32 results