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Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease.
Groves RW, Rauschmayr T, Nakamura K, Sarkar S, Williams IR, Kupper TS. Groves RW, et al. Among authors: kupper ts. J Clin Invest. 1996 Jul 15;98(2):336-44. doi: 10.1172/JCI118797. J Clin Invest. 1996. PMID: 8755642 Free PMC article.
Loss of nuclear pro-IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma.
Curiel-Lewandrowski C, Yamasaki H, Si CP, Jin X, Zhang Y, Richmond J, Tuzova M, Wilson K, Sullivan B, Jones D, Ryzhenko N, Little F, Kupper TS, Center DM, Cruikshank WW. Curiel-Lewandrowski C, et al. Among authors: kupper ts. J Clin Invest. 2011 Dec;121(12):4838-49. doi: 10.1172/JCI41769. Epub 2011 Nov 14. J Clin Invest. 2011. PMID: 22080865 Free PMC article. Retracted.
Human skin cells support thymus-independent T cell development.
Clark RA, Yamanaka K, Bai M, Dowgiert R, Kupper TS. Clark RA, et al. Among authors: kupper ts. J Clin Invest. 2005 Nov;115(11):3239-49. doi: 10.1172/JCI24731. Epub 2005 Oct 13. J Clin Invest. 2005. PMID: 16224538 Free PMC article.
The proteolytic activation of interleukin-1 beta.
Black R, Kronheim S, Sleath P, Greenstreet T, Virca GD, March C, Kupper T. Black R, et al. Agents Actions Suppl. 1991;35:85-9. Agents Actions Suppl. 1991. PMID: 1781425
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