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Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes.
Grotz S, Schäfer J, Wunderlich KA, Ellederova Z, Auch H, Bähr A, Runa-Vochozkova P, Fadl J, Arnold V, Ardan T, Veith M, Santamaria G, Dhom G, Hitzl W, Kessler B, Eckardt C, Klein J, Brymova A, Linnert J, Kurome M, Zakharchenko V, Fischer A, Blutke A, Döring A, Suchankova S, Popelar J, Rodríguez-Bocanegra E, Dlugaiczyk J, Straka H, May-Simera H, Wang W, Laugwitz KL, Vandenberghe LH, Wolf E, Nagel-Wolfrum K, Peters T, Motlik J, Fischer MD, Wolfrum U, Klymiuk N. Grotz S, et al. Among authors: kurome m. EMBO Mol Med. 2022 Apr 7;14(4):e14817. doi: 10.15252/emmm.202114817. Epub 2022 Mar 7. EMBO Mol Med. 2022. PMID: 35254721 Free PMC article.
Transgenic pigs as models for translational biomedical research.
Aigner B, Renner S, Kessler B, Klymiuk N, Kurome M, Wünsch A, Wolf E. Aigner B, et al. Among authors: kurome m. J Mol Med (Berl). 2010 Jul;88(7):653-64. doi: 10.1007/s00109-010-0610-9. Epub 2010 Mar 26. J Mol Med (Berl). 2010. PMID: 20339830 Review.
First inducible transgene expression in porcine large animal models.
Klymiuk N, Böcker W, Schönitzer V, Bähr A, Radic T, Fröhlich T, Wünsch A, Keßler B, Kurome M, Schilling E, Herbach N, Wanke R, Nagashima H, Mutschler W, Arnold GJ, Schwinzer R, Schieker M, Wolf E. Klymiuk N, et al. Among authors: kurome m. FASEB J. 2012 Mar;26(3):1086-99. doi: 10.1096/fj.11-185041. Epub 2011 Dec 1. FASEB J. 2012. PMID: 22138035
Sequential targeting of CFTR by BAC vectors generates a novel pig model of cystic fibrosis.
Klymiuk N, Mundhenk L, Kraehe K, Wuensch A, Plog S, Emrich D, Langenmayer MC, Stehr M, Holzinger A, Kröner C, Richter A, Kessler B, Kurome M, Eddicks M, Nagashima H, Heinritzi K, Gruber AD, Wolf E. Klymiuk N, et al. Among authors: kurome m. J Mol Med (Berl). 2012 May;90(5):597-608. doi: 10.1007/s00109-011-0839-y. Epub 2011 Dec 15. J Mol Med (Berl). 2012. PMID: 22170306
A porcine model of familial adenomatous polyposis.
Flisikowska T, Merkl C, Landmann M, Eser S, Rezaei N, Cui X, Kurome M, Zakhartchenko V, Kessler B, Wieland H, Rottmann O, Schmid RM, Schneider G, Kind A, Wolf E, Saur D, Schnieke A. Flisikowska T, et al. Among authors: kurome m. Gastroenterology. 2012 Nov;143(5):1173-1175.e7. doi: 10.1053/j.gastro.2012.07.110. Epub 2012 Aug 1. Gastroenterology. 2012. PMID: 22864254
Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs.
Leuchs S, Saalfrank A, Merkl C, Flisikowska T, Edlinger M, Durkovic M, Rezaei N, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Kind A, Wolf E, Schnieke A. Leuchs S, et al. Among authors: kurome m. PLoS One. 2012;7(10):e43323. doi: 10.1371/journal.pone.0043323. Epub 2012 Oct 5. PLoS One. 2012. PMID: 23071491 Free PMC article.
Permanent neonatal diabetes in INS(C94Y) transgenic pigs.
Renner S, Braun-Reichhart C, Blutke A, Herbach N, Emrich D, Streckel E, Wünsch A, Kessler B, Kurome M, Bähr A, Klymiuk N, Krebs S, Puk O, Nagashima H, Graw J, Blum H, Wanke R, Wolf E. Renner S, et al. Among authors: kurome m. Diabetes. 2013 May;62(5):1505-11. doi: 10.2337/db12-1065. Epub 2012 Dec 28. Diabetes. 2013. PMID: 23274907 Free PMC article.
85 results