Kurup P - Search Results

1

A STEP forward in neural function and degeneration.

Baum ML, Kurup P, Xu J, Lombroso PJ. Baum ML, et al. Among authors: kurup p. Commun Integr Biol. 2010 Sep;3(5):419-22. doi: 10.4161/cib.3.5.12692. Commun Integr Biol. 2010. PMID: 21057629 Free PMC article.

2

The role of STEP in Alzheimer's disease.

Kurup P, Zhang Y, Venkitaramani DV, Xu J, Lombroso PJ. Kurup P, et al. Channels (Austin). 2010 Sep-Oct;4(5):347-50. doi: 10.1523/JNEUROSCI.0157-10.2010. Epub 2010 Sep 6. Channels (Austin). 2010. PMID: 20699650 Free PMC article.

3

STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease.

Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC. Kurup PK, et al. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1202-7. doi: 10.1073/pnas.1417423112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583483 Free PMC article.

4

STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice.

Chatterjee M, Kurup PK, Lundbye CJ, Hugger Toft AK, Kwon J, Benedict J, Kamceva M, Banke TG, Lombroso PJ. Chatterjee M, et al. Neuropharmacology. 2018 Jan;128:43-53. doi: 10.1016/j.neuropharm.2017.09.026. Epub 2017 Sep 21. Neuropharmacology. 2018. PMID: 28943283

5

Inhibition of striatal-enriched protein tyrosine phosphatase (STEP) activity reverses behavioral deficits in a rodent model of autism.

Chatterjee M, Singh P, Xu J, Lombroso PJ, Kurup PK. Chatterjee M, et al. Among authors: kurup pk. Behav Brain Res. 2020 Aug 5;391:112713. doi: 10.1016/j.bbr.2020.112713. Epub 2020 May 24. Behav Brain Res. 2020. PMID: 32461127 Free PMC article.

6

The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications.

Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR, Yuan P, Chen G, Correa PR, Haroutunian V, Pittenger C, Lombroso PJ. Carty NC, et al. Among authors: kurup p. Transl Psychiatry. 2012 Jul 10;2(7):e137. doi: 10.1038/tp.2012.63. Transl Psychiatry. 2012. PMID: 22781170 Free PMC article.

7

Inhibition of STEP₆₁ ameliorates deficits in mouse and hiPSC-based schizophrenia models.

Xu J, Hartley BJ, Kurup P, Phillips A, Topol A, Xu M, Ononenyi C, Foscue E, Ho SM, Baguley TD, Carty N, Barros CS, Müller U, Gupta S, Gochman P, Rapoport J, Ellman JA, Pittenger C, Aronow B, Nairn AC, Nestor MW, Lombroso PJ, Brennand KJ. Xu J, et al. Among authors: kurup p. Mol Psychiatry. 2018 Feb;23(2):271-281. doi: 10.1038/mp.2016.163. Epub 2016 Oct 18. Mol Psychiatry. 2018. PMID: 27752082 Free PMC article.

8

The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.

Zhang Y, Venkitaramani DV, Gladding CM, Zhang Y, Kurup P, Molnar E, Collingridge GL, Lombroso PJ. Zhang Y, et al. Among authors: kurup p. J Neurosci. 2008 Oct 15;28(42):10561-6. doi: 10.1523/JNEUROSCI.2666-08.2008. J Neurosci. 2008. PMID: 18923032 Free PMC article.

9

Knockout of striatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation.

Venkitaramani DV, Paul S, Zhang Y, Kurup P, Ding L, Tressler L, Allen M, Sacca R, Picciotto MR, Lombroso PJ. Venkitaramani DV, et al. Among authors: kurup p. Synapse. 2009 Jan;63(1):69-81. doi: 10.1002/syn.20608. Synapse. 2009. PMID: 18932218 Free PMC article.

10

Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP.

Xu J, Kurup P, Zhang Y, Goebel-Goody SM, Wu PH, Hawasli AH, Baum ML, Bibb JA, Lombroso PJ. Xu J, et al. Among authors: kurup p. J Neurosci. 2009 Jul 22;29(29):9330-43. doi: 10.1523/JNEUROSCI.2212-09.2009. J Neurosci. 2009. PMID: 19625523 Free PMC article.

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