Kuryshev YA - Search Results

1

HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk.

Wible BA, Hawryluk P, Ficker E, Kuryshev YA, Kirsch G, Brown AM. Wible BA, et al. Among authors: kuryshev ya. J Pharmacol Toxicol Methods. 2005 Jul-Aug;52(1):136-45. doi: 10.1016/j.vascn.2005.03.008. J Pharmacol Toxicol Methods. 2005. PMID: 15950494

2

HERG channel trafficking.

Ficker E, Dennis A, Kuryshev Y, Wible BA, Brown AM. Ficker E, et al. Novartis Found Symp. 2005;266:57-69; discussion 70-4, 95-9. Novartis Found Symp. 2005. PMID: 16050262 Review.

3

Pentamidine-induced long QT syndrome and block of hERG trafficking.

Kuryshev YA, Ficker E, Wang L, Hawryluk P, Dennis AT, Wible BA, Brown AM, Kang J, Chen XL, Sawamura K, Reynolds W, Rampe D. Kuryshev YA, et al. J Pharmacol Exp Ther. 2005 Jan;312(1):316-23. doi: 10.1124/jpet.104.073692. Epub 2004 Aug 31. J Pharmacol Exp Ther. 2005. PMID: 15340016

4

Mechanisms of arsenic-induced prolongation of cardiac repolarization.

Ficker E, Kuryshev YA, Dennis AT, Obejero-Paz C, Wang L, Hawryluk P, Wible BA, Brown AM. Ficker E, et al. Among authors: kuryshev ya. Mol Pharmacol. 2004 Jul;66(1):33-44. doi: 10.1124/mol.66.1.33. Mol Pharmacol. 2004. PMID: 15213294

5

Antimony-based antileishmanial compounds prolong the cardiac action potential by an increase in cardiac calcium currents.

Kuryshev YA, Wang L, Wible BA, Wan X, Ficker E. Kuryshev YA, et al. Mol Pharmacol. 2006 Apr;69(4):1216-25. doi: 10.1124/mol.105.019281. Epub 2006 Jan 17. Mol Pharmacol. 2006. PMID: 16418337

6

An ion channel library for drug discovery and safety screening on automated platforms.

Wible BA, Kuryshev YA, Smith SS, Liu Z, Brown AM. Wible BA, et al. Among authors: kuryshev ya. Assay Drug Dev Technol. 2008 Dec;6(6):765-80. doi: 10.1089/adt.2008.171. Assay Drug Dev Technol. 2008. PMID: 19090691

7

Vanoxerine: cellular mechanism of a new antiarrhythmic.

Lacerda AE, Kuryshev YA, Yan GX, Waldo AL, Brown AM. Lacerda AE, et al. Among authors: kuryshev ya. J Cardiovasc Electrophysiol. 2010 Mar;21(3):301-10. doi: 10.1111/j.1540-8167.2009.01623.x. Epub 2009 Oct 8. J Cardiovasc Electrophysiol. 2010. PMID: 19817928 Free PMC article.

8

Increased cardiac risk in concomitant methadone and diazepam treatment: pharmacodynamic interactions in cardiac ion channels.

Kuryshev YA, Bruening-Wright A, Brown AM, Kirsch GE. Kuryshev YA, et al. J Cardiovasc Pharmacol. 2010 Oct;56(4):420-30. doi: 10.1097/FJC.0b013e3181f1d21b. J Cardiovasc Pharmacol. 2010. PMID: 20930594

9

MICE models: superior to the HERG model in predicting Torsade de Pointes.

Kramer J, Obejero-Paz CA, Myatt G, Kuryshev YA, Bruening-Wright A, Verducci JS, Brown AM. Kramer J, et al. Among authors: kuryshev ya. Sci Rep. 2013;3:2100. doi: 10.1038/srep02100. Sci Rep. 2013. PMID: 23812503 Free PMC article.

10

Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays.

Kuryshev YA, Brown AM, Duzic E, Kirsch GE. Kuryshev YA, et al. Assay Drug Dev Technol. 2014 Mar;12(2):110-9. doi: 10.1089/adt.2013.552. Epub 2014 Feb 28. Assay Drug Dev Technol. 2014. PMID: 24579774 Free PMC article.

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