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Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates.
Kusevic D, Kudithipudi S, Jeltsch A. Kusevic D, et al. J Biol Chem. 2016 Mar 18;291(12):6124-33. doi: 10.1074/jbc.M115.711952. Epub 2016 Jan 21. J Biol Chem. 2016. PMID: 26797129 Free PMC article.
Exploring the topology of the Gid complex, the E3 ubiquitin ligase involved in catabolite-induced degradation of gluconeogenic enzymes.
Menssen R, Schweiggert J, Schreiner J, Kusevic D, Reuther J, Braun B, Wolf DH. Menssen R, et al. Among authors: kusevic d. J Biol Chem. 2012 Jul 20;287(30):25602-14. doi: 10.1074/jbc.M112.363762. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645139 Free PMC article.
Non-radioactive protein lysine methyltransferase microplate assay based on reading domains.
Kudithipudi S, Kusevic D, Jeltsch A. Kudithipudi S, et al. Among authors: kusevic d. ChemMedChem. 2014 Mar;9(3):554-9. doi: 10.1002/cmdc.201300111. Epub 2013 May 13. ChemMedChem. 2014. PMID: 23671032
Activity and specificity of the human SUV39H2 protein lysine methyltransferase.
Schuhmacher MK, Kudithipudi S, Kusevic D, Weirich S, Jeltsch A. Schuhmacher MK, et al. Among authors: kusevic d. Biochim Biophys Acta. 2015 Jan;1849(1):55-63. doi: 10.1016/j.bbagrm.2014.11.005. Epub 2014 Nov 22. Biochim Biophys Acta. 2015. PMID: 25459750
Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays.
Kudithipudi S, Kusevic D, Weirich S, Jeltsch A. Kudithipudi S, et al. Among authors: kusevic d. J Vis Exp. 2014 Nov 29;(93):e52203. doi: 10.3791/52203. J Vis Exp. 2014. PMID: 25489813 Free PMC article.
Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase.
Weirich S, Kusevic D, Kudithipudi S, Jeltsch A. Weirich S, et al. Among authors: kusevic d. Sci Rep. 2015 Sep 22;5:13813. doi: 10.1038/srep13813. Sci Rep. 2015. PMID: 26391684 Free PMC article.
Clr4 specificity and catalytic activity beyond H3K9 methylation.
Kusevic D, Kudithipudi S, Iglesias N, Moazed D, Jeltsch A. Kusevic D, et al. Biochimie. 2017 Apr;135:83-88. doi: 10.1016/j.biochi.2017.01.013. Epub 2017 Jan 29. Biochimie. 2017. PMID: 28143796
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik P, Baude A, Mancarella D, Öz S, Kühn A, Toth R, Hey J, Toprak UH, Lim J, Nguyen VH, Jiang C, Mayakonda A, Hartmann M, Rosemann F, Breuer K, Vonficht D, Grünschläger F, Lee S, Schuhmacher MK, Kusevic D, Jauch A, Weichenhan D, Zustin J, Schlesner M, Haas S, Park JH, Park YJ, Oppermann U, Jeltsch A, Haller F, Fellenberg J, Lindroth AM, Plass C. Lutsik P, et al. Among authors: kusevic d. Nat Commun. 2020 Oct 27;11(1):5414. doi: 10.1038/s41467-020-18955-y. Nat Commun. 2020. PMID: 33110075 Free PMC article.