Kutok JL - Search Results

1

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Chan G, Cheung LS, Yang W, Milyavsky M, Sanders AD, Gu S, Hong WX, Liu AX, Wang X, Barbara M, Sharma T, Gavin J, Kutok JL, Iscove NN, Shannon KM, Dick JE, Neel BG, Braun BS. Chan G, et al. Among authors: kutok jl. Blood. 2011 Apr 21;117(16):4253-61. doi: 10.1182/blood-2010-11-319517. Epub 2011 Feb 25. Blood. 2011. PMID: 21398220 Free PMC article.

2

Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis.

Chan G, Kalaitzidis D, Usenko T, Kutok JL, Yang W, Mohi MG, Neel BG. Chan G, et al. Among authors: kutok jl. Blood. 2009 Apr 30;113(18):4414-24. doi: 10.1182/blood-2008-10-182626. Epub 2009 Jan 29. Blood. 2009. PMID: 19179468 Free PMC article.

3

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG. Araki T, et al. Among authors: kutok jl. Nat Med. 2004 Aug;10(8):849-57. doi: 10.1038/nm1084. Epub 2004 Jul 25. Nat Med. 2004. PMID: 15273746

4

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. Mohi MG, et al. Among authors: kutok jl. Cancer Cell. 2005 Feb;7(2):179-91. doi: 10.1016/j.ccr.2005.01.010. Cancer Cell. 2005. PMID: 15710330 Free article.

5

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

Pao LI, Lam KP, Henderson JM, Kutok JL, Alimzhanov M, Nitschke L, Thomas ML, Neel BG, Rajewsky K. Pao LI, et al. Among authors: kutok jl. Immunity. 2007 Jul;27(1):35-48. doi: 10.1016/j.immuni.2007.04.016. Epub 2007 Jun 28. Immunity. 2007. PMID: 17600736 Free article.

6

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

Koschmieder S, Göttgens B, Zhang P, Iwasaki-Arai J, Akashi K, Kutok JL, Dayaram T, Geary K, Green AR, Tenen DG, Huettner CS. Koschmieder S, et al. Among authors: kutok jl. Blood. 2005 Jan 1;105(1):324-34. doi: 10.1182/blood-2003-12-4369. Epub 2004 Aug 26. Blood. 2005. PMID: 15331442 Free article.

7

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. Kelly LM, et al. Among authors: kutok jl. Blood. 2002 Jan 1;99(1):310-8. doi: 10.1182/blood.v99.1.310. Blood. 2002. PMID: 11756186 Free article.

8

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.

Dutt S, Narla A, Lin K, Mullally A, Abayasekara N, Megerdichian C, Wilson FH, Currie T, Khanna-Gupta A, Berliner N, Kutok JL, Ebert BL. Dutt S, et al. Among authors: kutok jl. Blood. 2011 Mar 3;117(9):2567-76. doi: 10.1182/blood-2010-07-295238. Epub 2010 Nov 10. Blood. 2011. PMID: 21068437 Free PMC article.

9

Oncogenic K-ras cooperates with PML-RAR alpha to induce an acute promyelocytic leukemia-like disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Moore S, Shigematsu H, Ley TJ, Akashi K, Le Beau MM, Gilliland DG. Chan IT, et al. Among authors: kutok jl. Blood. 2006 Sep 1;108(5):1708-15. doi: 10.1182/blood-2006-04-015040. Epub 2006 May 4. Blood. 2006. PMID: 16675706 Free PMC article.

10

Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.

Tomasson MH, Williams IR, Li S, Kutok J, Cain D, Gillessen S, Dranoff G, Van Etten RA, Gilliland DG. Tomasson MH, et al. Blood. 2001 Mar 1;97(5):1435-41. doi: 10.1182/blood.v97.5.1435. Blood. 2001. PMID: 11222391 Free article.

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