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Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases.
Kuzin AP, Liu H, Kelly JA, Knox JR. Kuzin AP, et al. Biochemistry. 1995 Jul 25;34(29):9532-40. doi: 10.1021/bi00029a030. Biochemistry. 1995. PMID: 7626623
Crystallization and preliminary X-ray study of OXA-1, a class D beta-lactamase.
Sun T, Nukaga M, Mayama K, Crichlow GV, Kuzin AP, Knox JR. Sun T, et al. Among authors: kuzin ap. Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1912-4. doi: 10.1107/s0907444901016274. Epub 2001 Nov 21. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11717515
Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam.
Kuzin AP, Nukaga M, Nukaga Y, Hujer A, Bonomo RA, Knox JR. Kuzin AP, et al. Biochemistry. 2001 Feb 13;40(6):1861-6. doi: 10.1021/bi0022745. Biochemistry. 2001. PMID: 11327849
Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides.
Kuzin AP, Sun T, Jorczak-Baillass J, Healy VL, Walsh CT, Knox JR. Kuzin AP, et al. Structure. 2000 May 15;8(5):463-70. doi: 10.1016/s0969-2126(00)00129-5. Structure. 2000. PMID: 10801495
Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion.
Crichlow GV, Kuzin AP, Nukaga M, Mayama K, Sawai T, Knox JR. Crichlow GV, et al. Among authors: kuzin ap. Biochemistry. 1999 Aug 10;38(32):10256-61. doi: 10.1021/bi9908787. Biochemistry. 1999. PMID: 10441119
Structure of the SHV-1 beta-lactamase.
Kuzin AP, Nukaga M, Nukaga Y, Hujer AM, Bonomo RA, Knox JR. Kuzin AP, et al. Biochemistry. 1999 May 4;38(18):5720-7. doi: 10.1021/bi990136d. Biochemistry. 1999. PMID: 10231522
X-ray studies of enzymes that interact with penicillins.
Kelly JA, Kuzin AP, Charlier P, Fonzé E. Kelly JA, et al. Among authors: kuzin ap. Cell Mol Life Sci. 1998 Apr;54(4):353-8. doi: 10.1007/s000180050163. Cell Mol Life Sci. 1998. PMID: 9614972 Review.
The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 A resolution.
Kelly JA, Kuzin AP. Kelly JA, et al. Among authors: kuzin ap. J Mol Biol. 1995 Nov 24;254(2):223-36. doi: 10.1006/jmbi.1995.0613. J Mol Biol. 1995. PMID: 7490745
A bidirectional system for the dynamic small molecule control of intracellular fusion proteins.
Neklesa TK, Noblin DJ, Kuzin AP, Lew S, Seetharaman J, Acton TB, Kornhaber GJ, Xiao R, Montelione GT, Tong L, Crews CM. Neklesa TK, et al. Among authors: kuzin ap. ACS Chem Biol. 2013 Oct 18;8(10):2293-2300. doi: 10.1021/cb400569k. Epub 2013 Aug 26. ACS Chem Biol. 2013. PMID: 23978068 Free PMC article.
Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.
Héroux A, White EL, Ross LJ, Kuzin AP, Borhani DW. Héroux A, et al. Among authors: kuzin ap. Structure. 2000 Dec 15;8(12):1309-18. doi: 10.1016/s0969-2126(00)00546-3. Structure. 2000. PMID: 11188695
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