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Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Caria S, Hinds MG, Kvansakul M. Caria S, et al. Among authors: kvansakul m. Cell Death Dis. 2017 Jan 12;8(1):e2543. doi: 10.1038/cddis.2016.469. Cell Death Dis. 2017. PMID: 28079890 Free PMC article.
Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis.
Fischer SF, Ludwig H, Holzapfel J, Kvansakul M, Chen L, Huang DC, Sutter G, Knese M, H├Ącker G. Fischer SF, et al. Among authors: kvansakul m. Cell Death Differ. 2006 Jan;13(1):109-18. doi: 10.1038/sj.cdd.4401718. Cell Death Differ. 2006. PMID: 16003387
CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13.
Fairlie WD, Perugini MA, Kvansakul M, Chen L, Huang DC, Colman PM. Fairlie WD, et al. Among authors: kvansakul m. Cell Death Differ. 2006 Mar;13(3):426-34. doi: 10.1038/sj.cdd.4401762. Cell Death Differ. 2006. PMID: 16167070
A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Kvansakul M, van Delft MF, Lee EF, Gulbis JM, Fairlie WD, Huang DC, Colman PM. Kvansakul M, et al. Mol Cell. 2007 Mar 23;25(6):933-42. doi: 10.1016/j.molcel.2007.02.004. Mol Cell. 2007. PMID: 17386268
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.
Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DC, Colman PM. Kvansakul M, et al. Cell Death Differ. 2008 Oct;15(10):1564-71. doi: 10.1038/cdd.2008.83. Epub 2008 Jun 13. Cell Death Differ. 2008. PMID: 18551131
Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM. Kvansakul M, et al. PLoS Pathog. 2010 Dec 23;6(12):e1001236. doi: 10.1371/journal.ppat.1001236. PLoS Pathog. 2010. PMID: 21203485 Free PMC article.
Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.
Lay FT, Mills GD, Hulett MD, Kvansakul M. Lay FT, et al. Among authors: kvansakul m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jan 1;68(Pt 1):85-8. doi: 10.1107/S1744309111049530. Epub 2011 Dec 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22232180 Free PMC article.
Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis.
Lay FT, Veneer PK, Hulett MD, Kvansakul M. Lay FT, et al. Among authors: kvansakul m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Mar 1;68(Pt 3):314-6. doi: 10.1107/S1744309112001510. Epub 2012 Feb 22. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22442231 Free PMC article.
Dimerization of plant defensin NaD1 enhances its antifungal activity.
Lay FT, Mills GD, Poon IK, Cowieson NP, Kirby N, Baxter AA, van der Weerden NL, Dogovski C, Perugini MA, Anderson MA, Kvansakul M, Hulett MD. Lay FT, et al. Among authors: kvansakul m. J Biol Chem. 2012 Jun 8;287(24):19961-72. doi: 10.1074/jbc.M111.331009. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511788 Free PMC article.
Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria.
Brand IL, Civciristov S, Taylor NL, Talbo GH, Pantaki-Eimany D, Levina V, Clem RJ, Perugini MA, Kvansakul M, Hawkins CJ. Brand IL, et al. Among authors: kvansakul m. PLoS One. 2012;7(6):e39248. doi: 10.1371/journal.pone.0039248. Epub 2012 Jun 14. PLoS One. 2012. PMID: 22720082 Free PMC article.
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