Kvist T - Search Results

1

Effects of once-weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity.

Blundell J, Finlayson G, Axelsen M, Flint A, Gibbons C, Kvist T, Hjerpsted JB. Blundell J, et al. Among authors: kvist t. Diabetes Obes Metab. 2017 Sep;19(9):1242-1251. doi: 10.1111/dom.12932. Epub 2017 May 5. Diabetes Obes Metab. 2017. PMID: 28266779 Free PMC article. Clinical Trial.

2

Semaglutide improves postprandial glucose and lipid metabolism, and delays first-hour gastric emptying in subjects with obesity.

Hjerpsted JB, Flint A, Brooks A, Axelsen MB, Kvist T, Blundell J. Hjerpsted JB, et al. Among authors: kvist t. Diabetes Obes Metab. 2018 Mar;20(3):610-619. doi: 10.1111/dom.13120. Epub 2017 Oct 27. Diabetes Obes Metab. 2018. PMID: 28941314 Free PMC article. Clinical Trial.

3

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile.

Kragholm B, Kvist T, Madsen KK, Jørgensen L, Vogensen SB, Schousboe A, Clausen RP, Jensen AA, Bräuner-Osborne H. Kragholm B, et al. Among authors: kvist t. Biochem Pharmacol. 2013 Aug 15;86(4):521-8. doi: 10.1016/j.bcp.2013.06.007. Epub 2013 Jun 19. Biochem Pharmacol. 2013. PMID: 23792119

4

The four human gamma-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay.

Kvist T, Christiansen B, Jensen AA, Bräuner-Osborne H. Kvist T, et al. Comb Chem High Throughput Screen. 2009 Mar;12(3):241-9. doi: 10.2174/138620709787581684. Comb Chem High Throughput Screen. 2009. PMID: 19275529

5

Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors.

Kvist T, Greenwood JR, Hansen KB, Traynelis SF, Bräuner-Osborne H. Kvist T, et al. Neuropharmacology. 2013 Dec;75:324-36. doi: 10.1016/j.neuropharm.2013.08.003. Epub 2013 Aug 22. Neuropharmacology. 2013. PMID: 23973313 Free PMC article.

6

Structure-activity relationships for negative allosteric mGluR5 modulators.

Kaae BH, Harpsøe K, Kvist T, Mathiesen JM, Mølck C, Gloriam D, Jimenez HN, Uberti MA, Nielsen SM, Nielsen B, Bräuner-Osborne H, Sauerberg P, Clausen RP, Madsen U. Kaae BH, et al. Among authors: kvist t. ChemMedChem. 2012 Mar 5;7(3):440-51. doi: 10.1002/cmdc.201100578. Epub 2012 Jan 20. ChemMedChem. 2012. PMID: 22267204

7

The use of Xenopus oocytes in drug screening.

Kvist T, Hansen KB, Bräuner-Osborne H. Kvist T, et al. Expert Opin Drug Discov. 2011 Feb;6(2):141-53. doi: 10.1517/17460441.2011.546396. Epub 2011 Jan 18. Expert Opin Drug Discov. 2011. PMID: 22647133

8

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors.

Kristensen AS, Hansen KB, Naur P, Olsen L, Kurtkaya NL, Dravid SM, Kvist T, Yi F, Pøhlsgaard J, Clausen RP, Gajhede M, Kastrup JS, Traynelis SF. Kristensen AS, et al. Among authors: kvist t. Mol Pharmacol. 2016 Feb;89(2):253-62. doi: 10.1124/mol.115.100909. Epub 2015 Dec 10. Mol Pharmacol. 2016. PMID: 26661043 Free PMC article.

9

(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.

Pan Y, Gerasimov MR, Kvist T, Wellendorph P, Madsen KK, Pera E, Lee H, Schousboe A, Chebib M, Bräuner-Osborne H, Craft CM, Brodie JD, Schiffer WK, Dewey SL, Miller SR, Silverman RB. Pan Y, et al. Among authors: kvist t. J Med Chem. 2012 Jan 12;55(1):357-66. doi: 10.1021/jm201231w. Epub 2011 Dec 30. J Med Chem. 2012. PMID: 22128851 Free PMC article.

10

Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site.

Kvist T, Steffensen TB, Greenwood JR, Mehrzad Tabrizi F, Hansen KB, Gajhede M, Pickering DS, Traynelis SF, Kastrup JS, Bräuner-Osborne H. Kvist T, et al. J Biol Chem. 2013 Nov 15;288(46):33124-35. doi: 10.1074/jbc.M113.480210. Epub 2013 Sep 26. J Biol Chem. 2013. PMID: 24072709 Free PMC article.

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