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Candida albicans glutathione reductase downregulates Efg1-mediated cyclic AMP/protein kinase A pathway and leads to defective hyphal growth and virulence upon decreased cellular methylglyoxal content accompanied by activating alcohol dehydrogenase and glycolytic enzymes.
Ku M, Baek YU, Kwak MK, Kang SO. Ku M, et al. Among authors: kwak mk. Biochim Biophys Acta Gen Subj. 2017 Apr;1861(4):772-788. doi: 10.1016/j.bbagen.2016.10.010. Epub 2016 Oct 15. Biochim Biophys Acta Gen Subj. 2017. PMID: 27751952
222 results