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Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm.
Han YG, Kwok BH, Kernan MJ. Han YG, et al. Among authors: kwok bh. Curr Biol. 2003 Sep 30;13(19):1679-86. doi: 10.1016/j.cub.2003.08.034. Curr Biol. 2003. PMID: 14521833
The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5.
Kwok BH, Yang JG, Kapoor TM. Kwok BH, et al. Curr Biol. 2004 Oct 5;14(19):1783-8. doi: 10.1016/j.cub.2004.09.052. Curr Biol. 2004. PMID: 15458652
Microtubule flux: drivers wanted.
Kwok BH, Kapoor TM. Kwok BH, et al. Curr Opin Cell Biol. 2007 Feb;19(1):36-42. doi: 10.1016/ Epub 2006 Dec 15. Curr Opin Cell Biol. 2007. PMID: 17174541 Review.
Structural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity.
Laflamme G, Tremblay-Boudreault T, Roy MA, Andersen P, Bonneil É, Atchia K, Thibault P, D'Amours D, Kwok BH. Laflamme G, et al. Among authors: kwok bh. J Biol Chem. 2014 Oct 3;289(40):27418-31. doi: 10.1074/jbc.M114.569608. Epub 2014 Aug 18. J Biol Chem. 2014. PMID: 25135640 Free PMC article.
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.
Kapitein LC, Peterman EJ, Kwok BH, Kim JH, Kapoor TM, Schmidt CF. Kapitein LC, et al. Among authors: kwok bh. Nature. 2005 May 5;435(7038):114-8. doi: 10.1038/nature03503. Nature. 2005. PMID: 15875026
Allosteric inhibition of kinesin-5 modulates its processive directional motility.
Kwok BH, Kapitein LC, Kim JH, Peterman EJ, Schmidt CF, Kapoor TM. Kwok BH, et al. Nat Chem Biol. 2006 Sep;2(9):480-5. doi: 10.1038/nchembio812. Epub 2006 Aug 6. Nat Chem Biol. 2006. PMID: 16892050
Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis.
Kachaner D, Pinson X, El Kadhi KB, Normandin K, Talje L, Lavoie H, Lépine G, Carréno S, Kwok BH, Hickson GR, Archambault V. Kachaner D, et al. Among authors: kwok bh. J Cell Biol. 2014 Oct 27;207(2):201-11. doi: 10.1083/jcb.201408081. Epub 2014 Oct 20. J Cell Biol. 2014. PMID: 25332165 Free PMC article.
KIF14 binds tightly to microtubules and adopts a rigor-like conformation.
Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH. Arora K, et al. Among authors: kwok bh. J Mol Biol. 2014 Aug 26;426(17):2997-3015. doi: 10.1016/j.jmb.2014.05.030. Epub 2014 Jun 17. J Mol Biol. 2014. PMID: 24949858
DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases.
Talje L, Ben El Kadhi K, Atchia K, Tremblay-Boudreault T, Carreno S, Kwok BH. Talje L, et al. Among authors: kwok bh. FEBS Lett. 2014 Jun 27;588(14):2315-20. doi: 10.1016/j.febslet.2014.05.024. Epub 2014 May 22. FEBS Lett. 2014. PMID: 24859087
Microtubule cross-linking triggers the directional motility of kinesin-5.
Kapitein LC, Kwok BH, Weinger JS, Schmidt CF, Kapoor TM, Peterman EJ. Kapitein LC, et al. Among authors: kwok bh. J Cell Biol. 2008 Aug 11;182(3):421-8. doi: 10.1083/jcb.200801145. Epub 2008 Aug 4. J Cell Biol. 2008. PMID: 18678707 Free PMC article.
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