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593 results
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Highly protective antimalarial antibodies via precision library generation and yeast display screening.
Banach BB, Tripathi P, Da Silva Pereira L, Gorman J, Nguyen TD, Dillon M, Fahad AS, Kiyuka PK, Madan B, Wolfe JR, Bonilla B, Flynn B, Francica JR, Hurlburt NK, Kisalu NK, Liu T, Ou L, Rawi R, Schön A, Shen CH, Teng IT, Zhang B, Pancera M, Idris AH, Seder RA, Kwong PD, DeKosky BJ. Banach BB, et al. Among authors: kwong pd. J Exp Med. 2022 Aug 1;219(8):e20220323. doi: 10.1084/jem.20220323. Epub 2022 Jun 23. J Exp Med. 2022. PMID: 35736810
Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4.
Welles HC, King HAD, Nettey L, Cavett N, Gorman J, Zhou T, Tsybovsky Y, Du R, Song K, Nguyen R, Ambrozak D, Ransier A, Schramm CA, Doria-Rose NA, Swanstrom AE, Hoxie JA, LaBranche C, Montefiori DC, Douek DC, Kwong PD, Mascola JR, Roederer M, Mason RD. Welles HC, et al. Among authors: kwong pd. PLoS Pathog. 2022 Jun 16;18(6):e1010574. doi: 10.1371/journal.ppat.1010574. Online ahead of print. PLoS Pathog. 2022. PMID: 35709309
Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins.
Chonira V, Kwon YD, Gorman J, Case JB, Ku Z, Simeon R, Casner RG, Harris DR, Olia AS, Stephens T, Shapiro L, Boyd H, Tsybovsky Y, Krammer F, Diamond MS, Kwong PD, An Z, Chen Z. Chonira V, et al. Among authors: kwong pd. bioRxiv. 2022 May 31:2022.05.30.493765. doi: 10.1101/2022.05.30.493765. Preprint. bioRxiv. 2022. PMID: 35677079 Free PMC article.
Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.
Teng IT, Nazzari AF, Choe M, Liu T, Oliveira de Souza M, Petrova Y, Tsybovsky Y, Wang S, Zhang B, Artamonov M, Madan B, Huang A, Lopez Acevedo SN, Pan X, Ruckwardt TJ, DeKosky BJ, Mascola JR, Misasi J, Sullivan NJ, Zhou T, Kwong PD. Teng IT, et al. Among authors: kwong pd. PLoS One. 2022 May 24;17(5):e0268767. doi: 10.1371/journal.pone.0268767. eCollection 2022. PLoS One. 2022. PMID: 35609088 Free PMC article.
Tyrosine O-sulfation proteoforms affect HIV-1 monoclonal antibody potency.
Cai CX, Doria-Rose NA, Schneck NA, Ivleva VB, Tippett B, Shadrick WR, O'Connell S, Cooper JW, Schneiderman Z, Zhang B, Gowetski DB, Blackstock D, Demirji J, Lin BC, Gorman J, Liu T, Li Y, McDermott AB, Kwong PD, Carlton K, Gall JG, Lei QP. Cai CX, et al. Among authors: kwong pd. Sci Rep. 2022 May 19;12(1):8433. doi: 10.1038/s41598-022-12423-x. Sci Rep. 2022. PMID: 35589938 Free PMC article.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Westendorf K, Žentelis S, Wang L, Foster D, Vaillancourt P, Wiggin M, Lovett E, van der Lee R, Hendle J, Pustilnik A, Sauder JM, Kraft L, Hwang Y, Siegel RW, Chen J, Heinz BA, Higgs RE, Kallewaard NL, Jepson K, Goya R, Smith MA, Collins DW, Pellacani D, Xiang P, de Puyraimond V, Ricicova M, Devorkin L, Pritchard C, O'Neill A, Dalal K, Panwar P, Dhupar H, Garces FA, Cohen CA, Dye JM, Huie KE, Badger CV, Kobasa D, Audet J, Freitas JJ, Hassanali S, Hughes I, Munoz L, Palma HC, Ramamurthy B, Cross RW, Geisbert TW, Menachery V, Lokugamage K, Borisevich V, Lanz I, Anderson L, Sipahimalani P, Corbett KS, Yang ES, Zhang Y, Shi W, Zhou T, Choe M, Misasi J, Kwong PD, Sullivan NJ, Graham BS, Fernandez TL, Hansen CL, Falconer E, Mascola JR, Jones BE, Barnhart BC. Westendorf K, et al. Among authors: kwong pd. Cell Rep. 2022 May 17;39(7):110812. doi: 10.1016/j.celrep.2022.110812. Epub 2022 Apr 25. Cell Rep. 2022. PMID: 35568025 Free PMC article.
Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.
Cheung CS, Gorman J, Andrews SF, Rawi R, Reveiz M, Shen CH, Wang Y, Harris DR, Nazzari AF, Olia AS, Raab J, Teng IT, Verardi R, Wang S, Yang Y, Chuang GY, McDermott AB, Zhou T, Kwong PD. Cheung CS, et al. Among authors: kwong pd. Structure. 2022 Apr 19:S0969-2126(22)00130-7. doi: 10.1016/j.str.2022.04.003. Online ahead of print. Structure. 2022. PMID: 35489332
593 results