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When is an optimization not an optimization? Evaluation of clinical implications of information content (signal-to-noise ratio) in optimization of cardiac resynchronization therapy, and how to measure and maximize it.
Pabari PA, Willson K, Stegemann B, van Geldorp IE, Kyriacou A, Moraldo M, Mayet J, Hughes AD, Francis DP. Pabari PA, et al. Among authors: kyriacou a. Heart Fail Rev. 2011 May;16(3):277-90. doi: 10.1007/s10741-010-9203-5. Heart Fail Rev. 2011. PMID: 21110226 Free PMC article. Review.
A systematic approach to designing reliable VV optimization methodology: assessment of internal validity of echocardiographic, electrocardiographic and haemodynamic optimization of cardiac resynchronization therapy.
Kyriacou A, Li Kam Wa ME, Pabari PA, Unsworth B, Baruah R, Willson K, Peters NS, Kanagaratnam P, Hughes AD, Mayet J, Whinnett ZI, Francis DP. Kyriacou A, et al. Int J Cardiol. 2013 Aug 10;167(3):954-64. doi: 10.1016/j.ijcard.2012.03.086. Epub 2012 Mar 27. Int J Cardiol. 2013. PMID: 22459364 Free PMC article.
Improvement in coronary blood flow velocity with acute biventricular pacing is predominantly due to an increase in a diastolic backward-travelling decompression (suction) wave.
Kyriacou A, Whinnett ZI, Sen S, Pabari PA, Wright I, Cornelussen R, Lefroy D, Davies DW, Peters NS, Kanagaratnam P, Mayet J, Hughes AD, Francis DP, Davies JE. Kyriacou A, et al. Circulation. 2012 Sep 11;126(11):1334-44. doi: 10.1161/CIRCULATIONAHA.111.075606. Epub 2012 Aug 1. Circulation. 2012. PMID: 22855569 Clinical Trial.
125 results