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Year Number of Results
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146 results

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Page 1
Safety and Efficacy of Renal Denervation in Patients Taking Antihypertensive Medications.
Kandzari DE, Townsend RR, Kario K, Mahfoud F, Weber MA, Schmieder RE, Pocock S, Tsioufis K, Konstantinidis D, Choi J, East C, Lauder L, Cohen DL, Kobayashi T, Schmid A, Lee DP, Ma A, Weil J, Agdirlioglu T, Schlaich MP, Shetty S, Devireddy CM, Lea J, Aoki J, Sharp ASP, Anderson R, Fahy M, DeBruin V, Brar S, Böhm M; SPYRAL HTN-ON MED Investigators. Kandzari DE, et al. J Am Coll Cardiol. 2023 Nov 7;82(19):1809-1823. doi: 10.1016/j.jacc.2023.08.045. J Am Coll Cardiol. 2023. PMID: 37914510 Free article. Clinical Trial.
(SPYRAL HTN-ON MED Study [Global Clinical Study of Renal Denervation With the Symplicity Spyral Multi-electrode Renal Denervation System in Patients With Uncontrolled Hypertension in the Absence of Antihypertensive Medications]; NCT02439775)....
(SPYRAL HTN-ON MED Study [Global Clinical Study of Renal Denervation With the Symplicity Spyral Multi-electrode Renal Denervation System …
Future Anti-aldosterone Agents.
Dimitriadis K, Tsioufis C, Iliakis P, Kasiakogias A, Andrikou I, Leontsinis I, Konstantinidis D, Tousoulis D. Dimitriadis K, et al. Curr Pharm Des. 2018;24(46):5548-5554. doi: 10.2174/1381612825666190222145116. Curr Pharm Des. 2018. PMID: 30799785 Review.
BACKGROUND: Targeting the renin-angiotensin-aldosterone axis is one of the most important therapeutic pathways for blood pressure control, renal and cardiovascular protection. OBJECTIVE: In this review, the new nonsteroidal mineralcorticoid receptor antagonists will be pre …
BACKGROUND: Targeting the renin-angiotensin-aldosterone axis is one of the most important therapeutic pathways for blood pressure control, r …
Acute Effects of Electronic and Tobacco Cigarette Smoking on Sympathetic Nerve Activity and Blood Pressure in Humans.
Dimitriadis K, Narkiewicz K, Leontsinis I, Konstantinidis D, Mihas C, Andrikou I, Thomopoulos C, Tousoulis D, Tsioufis K. Dimitriadis K, et al. Int J Environ Res Public Health. 2022 Mar 9;19(6):3237. doi: 10.3390/ijerph19063237. Int J Environ Res Public Health. 2022. PMID: 35328926 Free PMC article. Clinical Trial.
We assessed the acute effects of TC, EC and sham smoking on blood pressure, heart rate and sympathetic nervous system. Methods: We studied 12 normotensive male habitual smokers (mean age 33 years) free of cardiovascular disease. ...
We assessed the acute effects of TC, EC and sham smoking on blood pressure, heart rate and sympathetic nervous system. Methods: We st …
Inflammatory Biomarkers in Hypertension.
Tsioufis P, Theofilis P, Dimitriadis K, Vlachakis PK, Iliakis P, Tsiachris D, Tsioufis K, Tousoulis D. Tsioufis P, et al. Among authors: dimitriadis k. Curr Med Chem. 2025;32(39):8751-8764. doi: 10.2174/0109298673348789250604113545. Curr Med Chem. 2025. PMID: 40671233 Review.
Hypertension remains a leading modifiable risk factor for cardiovascular diseases, yet its underlying mechanisms are not fully understood. Emerging evidence suggests that inflammation plays a central role in the pathogenesis and progression of hypertension. ...These biomar …
Hypertension remains a leading modifiable risk factor for cardiovascular diseases, yet its underlying mechanisms are not fully unders …
Lipoprotein(a) and aortic stenosis: Practical insights.
Dimitriadis K, Kyriakoulis KG, Pyrpyris N, Beneki E, Kamperidis V, Kollias A, Cenko E, Aznaouridis K, Aggeli K, Tsioufis K. Dimitriadis K, et al. Nutr Metab Cardiovasc Dis. 2025 Oct;35(10):104124. doi: 10.1016/j.numecd.2025.104124. Epub 2025 May 7. Nutr Metab Cardiovasc Dis. 2025. PMID: 40425406 Free article. Review.
AIMS: The role of Lp(a) in cardiovascular diseases is increasingly recognized, with high Lp(a) levels shown to be associated with worse outcomes. ...
AIMS: The role of Lp(a) in cardiovascular diseases is increasingly recognized, with high Lp(a) levels shown to be associated with wor …
Renal resistive index in hypertensive patients.
Andrikou I, Tsioufis C, Konstantinidis D, Kasiakogias A, Dimitriadis K, Leontsinis I, Andrikou E, Sanidas E, Kallikazaros I, Tousoulis D. Andrikou I, et al. Among authors: dimitriadis k. J Clin Hypertens (Greenwich). 2018 Dec;20(12):1739-1744. doi: 10.1111/jch.13410. Epub 2018 Oct 25. J Clin Hypertens (Greenwich). 2018. PMID: 30362245 Free PMC article. Review.
In essential hypertension, RRI is associated with subclinical markers of target organ damage and reflects renal disease progression beyond albuminuria and creatinine clearance. Also, RRI can estimate cardiovascular and renal risk. The evaluation of RRI may also help the th …
In essential hypertension, RRI is associated with subclinical markers of target organ damage and reflects renal disease progression beyond a …
Primary Aldosteronism: Novel Insights.
Stavropoulos K, Imprialos K, Papademetriou V, Faselis C, Tsioufis K, Dimitriadis K, Doumas M. Stavropoulos K, et al. Among authors: dimitriadis k. Curr Hypertens Rev. 2020;16(1):19-23. doi: 10.2174/1573402115666190415155512. Curr Hypertens Rev. 2020. PMID: 30987572 Review.
Patients with this endocrine syndrome are at increased cardiovascular risk, higher than hypertensive individuals with equal blood pressure levels. ...
Patients with this endocrine syndrome are at increased cardiovascular risk, higher than hypertensive individuals with equal blood pre …
Anabolic-Androgenic Steroids Induced Cardiomyopathy: A Narrative Review of the Literature.
Iliakis P, Stamou E, Kasiakogias A, Manta E, Sakalidis A, Vakka A, Theofilis P, Kourti FE, Konstantinidis D, Dimitriadis K, Vlachopoulos C, Tsioufis C. Iliakis P, et al. Among authors: dimitriadis k. Biomedicines. 2025 Sep 7;13(9):2190. doi: 10.3390/biomedicines13092190. Biomedicines. 2025. PMID: 41007753 Free PMC article. Review.
Although AASs affect multiple organ systems, their severe and potentially life-threatening complications involve the cardiovascular system. This review summarizes current knowledge on the pathophysiological mechanisms and clinical manifestations of AAS-induced cardi …
Although AASs affect multiple organ systems, their severe and potentially life-threatening complications involve the cardiovascular …
Coronary atherosclerotic plaque modification: the present and the future.
Theofilis P, Papanikolaou A, Karakasis P, Dimitriadis K, Vlachakis PK, Oikonomou E, Tsioufis K, Tousoulis D. Theofilis P, et al. Among authors: dimitriadis k. Expert Rev Cardiovasc Ther. 2025 Jan-Mar;23(3):65-71. doi: 10.1080/14779072.2025.2476132. Epub 2025 Mar 5. Expert Rev Cardiovasc Ther. 2025. PMID: 40040242 Review.
INTRODUCTION: Coronary atherosclerosis, marked by lipid deposition and inflammation, drives cardiovascular morbidity. Traditional treatments focus on lipid reduction, yet newer therapies target plaque composition, aiming to enhance stability and prevent coronary events. .. …
INTRODUCTION: Coronary atherosclerosis, marked by lipid deposition and inflammation, drives cardiovascular morbidity. Traditional tre …
146 results