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A thermostable Cas9 with increased lifetime in human plasma.
Harrington LB, Paez-Espino D, Staahl BT, Chen JS, Ma E, Kyrpides NC, Doudna JA. Harrington LB, et al. Among authors: kyrpides nc. Nat Commun. 2017 Nov 10;8(1):1424. doi: 10.1038/s41467-017-01408-4. Nat Commun. 2017. PMID: 29127284 Free PMC article.
Global metagenomic survey reveals a new bacterial candidate phylum in geothermal springs.
Eloe-Fadrosh EA, Paez-Espino D, Jarett J, Dunfield PF, Hedlund BP, Dekas AE, Grasby SE, Brady AL, Dong H, Briggs BR, Li WJ, Goudeau D, Malmstrom R, Pati A, Pett-Ridge J, Rubin EM, Woyke T, Kyrpides NC, Ivanova NN. Eloe-Fadrosh EA, et al. Among authors: kyrpides nc. Nat Commun. 2016 Jan 27;7:10476. doi: 10.1038/ncomms10476. Nat Commun. 2016. PMID: 26814032 Free PMC article.
The standard operating procedure of the DOE-JGI Metagenome Annotation Pipeline (MAP v.4).
Huntemann M, Ivanova NN, Mavromatis K, Tripp HJ, Paez-Espino D, Tennessen K, Palaniappan K, Szeto E, Pillay M, Chen IM, Pati A, Nielsen T, Markowitz VM, Kyrpides NC. Huntemann M, et al. Among authors: kyrpides nc. Stand Genomic Sci. 2016 Feb 24;11:17. doi: 10.1186/s40793-016-0138-x. eCollection 2016. Stand Genomic Sci. 2016. PMID: 26918089 Free PMC article.
Uncovering Earth's virome.
Paez-Espino D, Eloe-Fadrosh EA, Pavlopoulos GA, Thomas AD, Huntemann M, Mikhailova N, Rubin E, Ivanova NN, Kyrpides NC. Paez-Espino D, et al. Among authors: kyrpides nc. Nature. 2016 Aug 25;536(7617):425-30. doi: 10.1038/nature19094. Epub 2016 Aug 17. Nature. 2016. PMID: 27533034
IMG/VR: a database of cultured and uncultured DNA Viruses and retroviruses.
Paez-Espino D, Chen IA, Palaniappan K, Ratner A, Chu K, Szeto E, Pillay M, Huang J, Markowitz VM, Nielsen T, Huntemann M, K Reddy TB, Pavlopoulos GA, Sullivan MB, Campbell BJ, Chen F, McMahon K, Hallam SJ, Denef V, Cavicchioli R, Caffrey SM, Streit WR, Webster J, Handley KM, Salekdeh GH, Tsesmetzis N, Setubal JC, Pope PB, Liu WT, Rivers AR, Ivanova NN, Kyrpides NC. Paez-Espino D, et al. Among authors: kyrpides nc. Nucleic Acids Res. 2017 Jan 4;45(D1):D457-D465. doi: 10.1093/nar/gkw1030. Epub 2016 Oct 30. Nucleic Acids Res. 2017. PMID: 27799466 Free PMC article.
1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life.
Mukherjee S, Seshadri R, Varghese NJ, Eloe-Fadrosh EA, Meier-Kolthoff JP, Göker M, Coates RC, Hadjithomas M, Pavlopoulos GA, Paez-Espino D, Yoshikuni Y, Visel A, Whitman WB, Garrity GM, Eisen JA, Hugenholtz P, Pati A, Ivanova NN, Woyke T, Klenk HP, Kyrpides NC. Mukherjee S, et al. Among authors: kyrpides nc. Nat Biotechnol. 2017 Jul;35(7):676-683. doi: 10.1038/nbt.3886. Epub 2017 Jun 12. Nat Biotechnol. 2017. PMID: 28604660
On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires.
Silas S, Makarova KS, Shmakov S, Páez-Espino D, Mohr G, Liu Y, Davison M, Roux S, Krishnamurthy SR, Fu BXH, Hansen LL, Wang D, Sullivan MB, Millard A, Clokie MR, Bhaya D, Lambowitz AM, Kyrpides NC, Koonin EV, Fire AZ. Silas S, et al. Among authors: kyrpides nc. mBio. 2017 Jul 11;8(4):e00897-17. doi: 10.1128/mBio.00897-17. mBio. 2017. PMID: 28698278 Free PMC article.
690 results