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Synthesis and evaluation of 9-hydroxy-5-methyl-(and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazole-1-N- [(dialkylamino)alkyl]carboxamides, a new promising series of antitumor olivacine derivatives.
Jasztold-Howorko R, Landras C, Pierré A, Atassi G, Guilbaud N, Kraus-Berthier L, Léonce S, Rolland Y, Prost JF, Bisagni E. Jasztold-Howorko R, et al. Among authors: leonce s. J Med Chem. 1994 Jul 22;37(15):2445-52. doi: 10.1021/jm00041a024. J Med Chem. 1994. PMID: 8057291
Synthesis of 9-O-substituted derivatives of 9-hydroxy-5, 6-dimethyl-6H-pyrido[4,3-b]carbazole-1-carboxylic acid (2-(dimethylamino)ethyl)amide and their 10- and 11-methyl analogues with improved antitumor activity.
Guillonneau C, PierréA, Charton Y, Guilbaud N, Kraus-Berthier L, Léonce S, Michel A, Bisagni E, Atassi G. Guillonneau C, et al. Among authors: leonce s. J Med Chem. 1999 Jun 17;42(12):2191-203. doi: 10.1021/jm981093m. J Med Chem. 1999. PMID: 10377224
127 results