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Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator.
Kitao T, Lepine F, Babloudi S, Walte F, Steinbacher S, Maskos K, Blaesse M, Negri M, Pucci M, Zahler B, Felici A, Rahme LG. Kitao T, et al. Among authors: lepine f. mBio. 2018 Jan 16;9(1):e02158-17. doi: 10.1128/mBio.02158-17. mBio. 2018. PMID: 29339431 Free PMC article.
Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance.
Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Déziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lépine F, Rahme LG. Maura D, et al. ACS Chem Biol. 2017 May 19;12(5):1435-1443. doi: 10.1021/acschembio.6b01139. Epub 2017 Apr 12. ACS Chem Biol. 2017. PMID: 28379691
Production of rhamnolipids by Pseudomonas aeruginosa.
Soberón-Chávez G, Lépine F, Déziel E. Soberón-Chávez G, et al. Appl Microbiol Biotechnol. 2005 Oct;68(6):718-25. doi: 10.1007/s00253-005-0150-3. Epub 2005 Oct 13. Appl Microbiol Biotechnol. 2005. PMID: 16160828 Review.
Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity.
Starkey M, Lepine F, Maura D, Bandyopadhaya A, Lesic B, He J, Kitao T, Righi V, Milot S, Tzika A, Rahme L. Starkey M, et al. PLoS Pathog. 2014 Aug 21;10(8):e1004321. doi: 10.1371/journal.ppat.1004321. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25144274 Free PMC article.
Cassava wastewater as a substrate for the simultaneous production of rhamnolipids and polyhydroxyalkanoates by Pseudomonas aeruginosa.
Costa SG, Lépine F, Milot S, Déziel E, Nitschke M, Contiero J. Costa SG, et al. J Ind Microbiol Biotechnol. 2009 Aug;36(8):1063-72. doi: 10.1007/s10295-009-0590-3. Epub 2009 May 27. J Ind Microbiol Biotechnol. 2009. PMID: 19471980
Monorhamnolipids and 3-(3-hydroxyalkanoyloxy)alkanoic acids (HAAs) production using Escherichia coli as a heterologous host.
Cabrera-Valladares N, Richardson AP, Olvera C, Treviño LG, Déziel E, Lépine F, Soberón-Chávez G. Cabrera-Valladares N, et al. Appl Microbiol Biotechnol. 2006 Nov;73(1):187-94. doi: 10.1007/s00253-006-0468-5. Epub 2006 Jun 8. Appl Microbiol Biotechnol. 2006. PMID: 16847602
Catecholate siderophore esterases Fes, IroD and IroE are required for salmochelins secretion following utilization, but only IroD contributes to virulence of extra-intestinal pathogenic Escherichia coli.
Caza M, Garénaux A, Lépine F, Dozois CM. Caza M, et al. Mol Microbiol. 2015 Aug;97(4):717-32. doi: 10.1111/mmi.13059. Epub 2015 Jun 6. Mol Microbiol. 2015. PMID: 25982934
The end of an old hypothesis: the pseudomonas signaling molecules 4-hydroxy-2-alkylquinolines derive from fatty acids, not 3-ketofatty acids.
Dulcey CE, Dekimpe V, Fauvelle DA, Milot S, Groleau MC, Doucet N, Rahme LG, Lépine F, Déziel E. Dulcey CE, et al. Chem Biol. 2013 Dec 19;20(12):1481-91. doi: 10.1016/j.chembiol.2013.09.021. Epub 2013 Nov 14. Chem Biol. 2013. PMID: 24239007 Free PMC article.
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