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Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis.

López-Hernández T, Puchkov D, Krause E, Maritzen T, Haucke V. López-Hernández T, et al. Nat Cell Biol. 2020 Jul;22(7):815-827. doi: 10.1038/s41556-020-0535-7. Epub 2020 Jun 29. Nat Cell Biol. 2020. PMID: 32601373

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Endocytosis in the adaptation to cellular stress.

López-Hernández T, Haucke V, Maritzen T. López-Hernández T, et al. Cell Stress. 2020 Aug 18;4(10):230-247. doi: 10.15698/cst2020.10.232. Cell Stress. 2020. PMID: 33024932 Free PMC article. Review.

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Megalencephalic leukoencephalopathy with subcortical cysts: A personal biochemical retrospective.

Estévez R, Elorza-Vidal X, Gaitán-Peñas H, Pérez-Rius C, Armand-Ugón M, Alonso-Gardón M, Xicoy-Espaulella E, Sirisi S, Arnedo T, Capdevila-Nortes X, López-Hernández T, Montolio M, Duarri A, Teijido O, Barrallo-Gimeno A, Palacín M, Nunes V. Estévez R, et al. Among authors: lopez hernandez t. Eur J Med Genet. 2018 Jan;61(1):50-60. doi: 10.1016/j.ejmg.2017.10.013. Epub 2017 Oct 25. Eur J Med Genet. 2018. PMID: 29079544 Review.

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Ramping up the autophagy-lysosome system to cope with osmotic stress.

López-Hernández T, Maritzen T, Haucke V. López-Hernández T, et al. Autophagy. 2020 Oct;16(10):1921-1922. doi: 10.1080/15548627.2020.1798065. Epub 2020 Aug 4. Autophagy. 2020. PMID: 32684085 Free PMC article.

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Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.

Azarnia Tehran D, López-Hernández T, Maritzen T. Azarnia Tehran D, et al. Among authors: lopez hernandez t. Cells. 2019 Oct 29;8(11):1345. doi: 10.3390/cells8111345. Cells. 2019. PMID: 31671891 Free PMC article. Review.

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Lysosomal Dysfunction Caused by Cellular Accumulation of Silica Nanoparticles.

Schütz I, Lopez-Hernandez T, Gao Q, Puchkov D, Jabs S, Nordmeyer D, Schmudde M, Rühl E, Graf CM, Haucke V. Schütz I, et al. Among authors: lopez hernandez t. J Biol Chem. 2016 Jul 1;291(27):14170-14184. doi: 10.1074/jbc.M115.710947. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226546 Free PMC article.

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Control of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations.

Xu H, Isenmann S, López-Hernández T, Estévez R, Lukacs GL, Apaja PM. Xu H, et al. Among authors: lopez hernandez t. Sci Rep. 2021 Sep 16;11(1):18435. doi: 10.1038/s41598-021-97777-4. Sci Rep. 2021. PMID: 34531445 Free PMC article.

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Functional analyses of mutations in HEPACAM causing megalencephalic leukoencephalopathy.

Arnedo T, López-Hernández T, Jeworutzki E, Capdevila-Nortes X, Sirisi S, Pusch M, Estévez R. Arnedo T, et al. Among authors: lopez hernandez t. Hum Mutat. 2014 Oct;35(10):1175-8. doi: 10.1002/humu.22622. Epub 2014 Aug 18. Hum Mutat. 2014. PMID: 25044933

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A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy.

Helbig I, Lopez-Hernandez T, Shor O, Galer P, Ganesan S, Pendziwiat M, Rademacher A, Ellis CA, Hümpfer N, Schwarz N, Seiffert S, Peeden J, Shen J, Štěrbová K, Hammer TB, Møller RS, Shinde DN, Tang S, Smith L, Poduri A, Krause R, Benninger F, Helbig KL, Haucke V, Weber YG; EuroEPINOMICS-RES Consortium; GRIN Consortium. Helbig I, et al. Among authors: lopez hernandez t. Am J Hum Genet. 2019 Jun 6;104(6):1060-1072. doi: 10.1016/j.ajhg.2019.04.001. Epub 2019 May 16. Am J Hum Genet. 2019. PMID: 31104773 Free PMC article.

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Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.

López-Hernández T, Takenaka KI, Mori Y, Kongpracha P, Nagamori S, Haucke V, Takamori S. López-Hernández T, et al. Elife. 2022 Jan 11;11:e71198. doi: 10.7554/eLife.71198. Elife. 2022. PMID: 35014951 Free PMC article.

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