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Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease.
Heller GT, Aprile FA, Michaels TCT, Limbocker R, Perni M, Ruggeri FS, Mannini B, Löhr T, Bonomi M, Camilloni C, De Simone A, Felli IC, Pierattelli R, Knowles TPJ, Dobson CM, Vendruscolo M. Heller GT, et al. Among authors: lohr t. Sci Adv. 2020 Nov 4;6(45):eabb5924. doi: 10.1126/sciadv.abb5924. Print 2020 Nov. Sci Adv. 2020. PMID: 33148639 Free PMC article.
A kinetic ensemble of the Alzheimer's Aβ peptide.
Löhr T, Kohlhoff K, Heller GT, Camilloni C, Vendruscolo M. Löhr T, et al. Nat Comput Sci. 2021 Jan;1(1):71-78. doi: 10.1038/s43588-020-00003-w. Epub 2021 Jan 14. Nat Comput Sci. 2021. PMID: 38217162
Effects of α-tubulin acetylation on microtubule structure and stability.
Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Löhr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E. Eshun-Wilson L, et al. Among authors: lohr t. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10366-10371. doi: 10.1073/pnas.1900441116. Epub 2019 May 9. Proc Natl Acad Sci U S A. 2019. PMID: 31072936 Free PMC article.
58 results