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Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications.
Meade BR, Gogoi K, Hamil AS, Palm-Apergi C, van den Berg A, Hagopian JC, Springer AD, Eguchi A, Kacsinta AD, Dowdy CF, Presente A, Lönn P, Kaulich M, Yoshioka N, Gros E, Cui XS, Dowdy SF. Meade BR, et al. Among authors: lonn p. Nat Biotechnol. 2014 Dec;32(12):1256-61. doi: 10.1038/nbt.3078. Epub 2014 Nov 17. Nat Biotechnol. 2014. PMID: 25402614 Free PMC article.
Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase.
Lönn P, Vanlandewijck M, Raja E, Kowanetz M, Watanabe Y, Kowanetz K, Vasilaki E, Heldin CH, Moustakas A. Lönn P, et al. J Biol Chem. 2012 Apr 13;287(16):12867-78. doi: 10.1074/jbc.M111.307249. Epub 2012 Feb 29. J Biol Chem. 2012. PMID: 22378783 Free PMC article.
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