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Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists.
Stahn C, Löwenberg M, Hommes DW, Buttgereit F. Stahn C, et al. Among authors: lowenberg m. Mol Cell Endocrinol. 2007 Sep 15;275(1-2):71-8. doi: 10.1016/j.mce.2007.05.019. Epub 2007 Jun 2. Mol Cell Endocrinol. 2007. PMID: 17630118 Review.
., Eisenacher, M., Nordhues, U., Sorg, C., Sunderkotter, C., Roth, J., 2007. Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes. ...
., Eisenacher, M., Nordhues, U., Sorg, C., Sunderkotter, C., Roth, J., 2007. Glucocorticoids induce differentiation of a specifically …
Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling.
Löwenberg M, Tuynman J, Scheffer M, Verhaar A, Vermeulen L, van Deventer S, Hommes D, Peppelenbosch M. Löwenberg M, et al. Endocrinology. 2006 Jul;147(7):3555-62. doi: 10.1210/en.2005-1602. Epub 2006 Mar 30. Endocrinology. 2006. PMID: 16574792
Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression.
Löwenberg M, Verhaar AP, van den Brink GR, Hommes DW. Löwenberg M, et al. Trends Mol Med. 2007 Apr;13(4):158-63. doi: 10.1016/j.molmed.2007.02.001. Epub 2007 Feb 9. Trends Mol Med. 2007. PMID: 17293163 Review.
Origin and functional activity of the membrane-bound glucocorticoid receptor.
Strehl C, Gaber T, Löwenberg M, Hommes DW, Verhaar AP, Schellmann S, Hahne M, Fangradt M, Wagegg M, Hoff P, Scheffold A, Spies CM, Burmester GR, Buttgereit F. Strehl C, et al. Among authors: lowenberg m. Arthritis Rheum. 2011 Dec;63(12):3779-88. doi: 10.1002/art.30637. Arthritis Rheum. 2011. PMID: 21898343
Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands.
Löwenberg M, Stahn C, Hommes DW, Buttgereit F. Löwenberg M, et al. Steroids. 2008 Oct;73(9-10):1025-9. doi: 10.1016/j.steroids.2007.12.002. Epub 2007 Dec 14. Steroids. 2008. PMID: 18221974 Review.
Superantigen-induced steroid resistance depends on activation of phospholipase Cβ2.
Verhaar AP, Wildenberg ME, Duijvestein M, Vos AC, Peppelenbosch MP, Löwenberg M, Hommes DW, van den Brink GR. Verhaar AP, et al. Among authors: lowenberg m. J Immunol. 2013 Jun 15;190(12):6589-95. doi: 10.4049/jimmunol.1202898. Epub 2013 May 20. J Immunol. 2013. PMID: 23690479
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN.
Löwenberg M, Verhaar AP, Bilderbeek J, Marle Jv, Buttgereit F, Peppelenbosch MP, van Deventer SJ, Hommes DW. Löwenberg M, et al. EMBO Rep. 2006 Oct;7(10):1023-9. doi: 10.1038/sj.embor.7400775. Epub 2006 Aug 4. EMBO Rep. 2006. PMID: 16888650 Free PMC article.
Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn.
Löwenberg M, Tuynman J, Bilderbeek J, Gaber T, Buttgereit F, van Deventer S, Peppelenbosch M, Hommes D. Löwenberg M, et al. Blood. 2005 Sep 1;106(5):1703-10. doi: 10.1182/blood-2004-12-4790. Epub 2005 May 17. Blood. 2005. PMID: 15899916
Proximal signaling molecules as potential targets for anti-inflammatory therapy.
Löwenberg M. Löwenberg M. Curr Opin Drug Discov Devel. 2007 Sep;10(5):560-4. Curr Opin Drug Discov Devel. 2007. PMID: 17786854 Review.
Optimization of anti-TNF therapy in patients with Inflammatory Bowel Disease.
Strik AS, Bots SJ, D'Haens G, Löwenberg M. Strik AS, et al. Among authors: lowenberg m. Expert Rev Clin Pharmacol. 2016;9(3):429-39. doi: 10.1586/17512433.2016.1133288. Epub 2016 Jan 28. Expert Rev Clin Pharmacol. 2016. PMID: 26681400 Review.
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