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The incidence of transient infantile pseudohypoaldosteronism in Ireland: A prospective study.
Kaninde A, Grace ML, Joyce C, Taylor NF, Ghataore L, Riordan MF, O'Grady MJ, O'Connell SM. Kaninde A, et al. Among authors: ghataore l. Acta Paediatr. 2021 Apr;110(4):1257-1263. doi: 10.1111/apa.15688. Epub 2021 Feb 2. Acta Paediatr. 2021. PMID: 33245792
Infants under one year of age presenting for the first time with hyponatraemia (Na < 130 mmol/L) and/or hyperkalaemia (K > 5.0 mmol/L) associated with urosepsis/UTM were reported. ...

Infants under one year of age presenting for the first time with hyponatraemia (Na < 130 mmol/L) and/or hyperkalaemia (K > 5.0

…
Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells.
Ruiz-Babot G, Balyura M, Hadjidemetriou I, Ajodha SJ, Taylor DR, Ghataore L, Taylor NF, Schubert U, Ziegler CG, Storr HL, Druce MR, Gevers EF, Drake WM, Srirangalingam U, Conway GS, King PJ, Metherell LA, Bornstein SR, Guasti L. Ruiz-Babot G, et al. Among authors: ghataore l. Cell Rep. 2018 Jan 30;22(5):1236-1249. doi: 10.1016/j.celrep.2018.01.003. Cell Rep. 2018. PMID: 29386111 Free PMC article.
The impact of mitotane therapy on serum-free proteins in patients with adrenocortical carcinoma.
Lech M, Ranasinghe R, Vincent RP, Taylor DR, Ghataore L, Luxton J, Lajeunesse-Trempe F, Roser P, Drakou EE, Chuah LL, Grossman AB, Aylwin SJB, Dimitriadis GK. Lech M, et al. Among authors: ghataore l. Endocr Connect. 2024 Feb 12;13(3):e230159. doi: 10.1530/EC-23-0159. Print 2024 Mar 1. Endocr Connect. 2024. PMID: 38236710 Free PMC article.
RESULTS: Patients on mitotane therapy had a higher mean serum CBG concentration compared to the adrenal neoplasm group (sub-therapeutic: 79.5 (95% CI: 33.6, 125.4 nmol/L), therapeutic: 85.3 (95% CI: 37.1-133.6 nmol/L), supra-therapeutic: 75.7 (95% CI: -19.3, 170.6 n …
RESULTS: Patients on mitotane therapy had a higher mean serum CBG concentration compared to the adrenal neoplasm group (sub-therapeutic: 79. …
Low Baseline but Not Delta Cortisol Relates to 28-Day Transplant-Free Survival in Acute and Acute-on-Chronic Liver Failure.
Roth S, Flint E, Ghataore L, Patel VC, Singanayagam A, Vincent RP, Triantafyllou E, Ma Y, Bernal W, Auzinger G, Heneghan M, Antoniades C, Christ-Crain M, McPhail MJW, Taylor DR, Wendon J, Bernsmeier C. Roth S, et al. Among authors: ghataore l. Gastro Hep Adv. 2022 Sep 5;2(1):72-82. doi: 10.1016/j.gastha.2022.08.006. eCollection 2023. Gastro Hep Adv. 2022. PMID: 39130154 Free PMC article.
RESULTS: In ALF, baseline cortisol concentrations <387 nmol/L predicted TFS (sensitivity 83%, specificity 53%). In ACLF, baseline cortisol <392 nmol/L correlated with TFS (sensitivity 80%, specificity 61%). ...However, in patients with baseline cortisol exceed …
RESULTS: In ALF, baseline cortisol concentrations <387 nmol/L predicted TFS (sensitivity 83%, specificity 53%). In ACLF, baseline …
Effects of mitotane treatment on human steroid metabolism: implications for patient management.
Ghataore L, Chakraborti I, Aylwin SJ, Schulte KM, Dworakowska D, Coskeran P, Taylor NF. Ghataore L, et al. Endocr Connect. 2012 Jul 21;1(1):37-47. doi: 10.1530/EC-12-0028. Print 2012 Jul 1. Endocr Connect. 2012. PMID: 23781302 Free PMC article.
Samples were collected after plasma mitotane had reached the therapeutic range of 14-20 mg/l. Increased excretion of polar unconjugated steroids during mitotane treatment was confirmed, with 6beta-hydroxycortisol and 6beta-hydroxy-20-dihydrocortisols predominating. ...
Samples were collected after plasma mitotane had reached the therapeutic range of 14-20 mg/l. Increased excretion of polar unconjugat …