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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1916 2
1917 3
1924 1
1925 3
1928 2
1929 1
1930 6
1931 1
1932 2
1934 1
1935 1
1937 1
1938 2
1939 1
1940 4
1941 1
1942 2
1943 1
1944 2
1945 6
1946 16
1947 10
1948 21
1949 9
1950 16
1951 34
1952 46
1953 58
1954 53
1955 63
1956 103
1957 123
1958 105
1959 104
1960 123
1961 132
1962 160
1963 293
1964 449
1965 310
1966 299
1967 367
1968 451
1969 575
1970 549
1971 690
1972 682
1973 626
1974 738
1975 870
1976 786
1977 833
1978 780
1979 819
1980 944
1981 915
1982 1052
1983 1119
1984 1212
1985 1278
1986 1464
1987 1311
1988 1463
1989 1610
1990 1828
1991 2099
1992 2687
1993 2975
1994 3473
1995 3722
1996 3716
1997 3965
1998 3968
1999 3890
2000 3915
2001 3690
2002 3774
2003 3806
2004 3894
2005 4068
2006 4177
2007 4252
2008 4101
2009 3976
2010 4032
2011 4156
2012 4138
2013 4148
2014 4007
2015 3911
2016 3806
2017 3757
2018 3758
2019 3876
2020 4100
2021 4159
2022 4040
2023 3946
2024 4158
2025 4712
2026 3118

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152,067 results

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Page 1
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
Geiger R, Rieckmann JC, Wolf T, Basso C, Feng Y, Fuhrer T, Kogadeeva M, Picotti P, Meissner F, Mann M, Zamboni N, Sallusto F, Lanzavecchia A. Geiger R, et al. Cell. 2016 Oct 20;167(3):829-842.e13. doi: 10.1016/j.cell.2016.09.031. Epub 2016 Oct 13. Cell. 2016. PMID: 27745970 Free PMC article.
We discovered critical changes in the arginine metabolism that led to a drop in intracellular L-arginine concentration. Elevating L-arginine levels induced global metabolic changes including a shift from glycolysis to oxidative phosphorylation i …
We discovered critical changes in the arginine metabolism that led to a drop in intracellular L-arginine concentration. …
L-Arginine in diabetes: clinical and preclinical evidence.
Forzano I, Avvisato R, Varzideh F, Jankauskas SS, Cioppa A, Mone P, Salemme L, Kansakar U, Tesorio T, Trimarco V, Santulli G. Forzano I, et al. Cardiovasc Diabetol. 2023 Apr 18;22(1):89. doi: 10.1186/s12933-023-01827-2. Cardiovasc Diabetol. 2023. PMID: 37072850 Free PMC article. Review.
L-Arginine (L-Arg), is a semi-essential amino acid involved in the formation of nitric oxide. ...
L-Arginine (L-Arg), is a semi-essential amino acid involved in the formation of nitric oxide. ...
L-arginine metabolism as pivotal interface of mutual host-microbe interactions in the gut.
Nüse B, Holland T, Rauh M, Gerlach RG, Mattner J. Nüse B, et al. Gut Microbes. 2023 Jan-Dec;15(1):2222961. doi: 10.1080/19490976.2023.2222961. Gut Microbes. 2023. PMID: 37358082 Free PMC article. Review.
L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in mammalian and microbial organisms. ...
L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in mammalian and microbial organisms. …
l-Arginine: A multifaceted regulator of diabetic cardiomyopathy.
Thakur MR, Tupe RS. Thakur MR, et al. Biochem Biophys Res Commun. 2025 May 1;761:151720. doi: 10.1016/j.bbrc.2025.151720. Epub 2025 Mar 28. Biochem Biophys Res Commun. 2025. PMID: 40186920 Review.
Accelerated glycation, oxidative stress, and activated inflammatory pathways culminate in cardiac fibrosis and hypertrophy in DCM. The regulatory effects of l-Arginine (L-Arg) have been elucidated in the pathological changes of DCM, including myocardial fibro …
Accelerated glycation, oxidative stress, and activated inflammatory pathways culminate in cardiac fibrosis and hypertrophy in DCM. The regul …
l-arginine production in Corynebacterium glutamicum: manipulation and optimization of the metabolic process.
Jiang Y, Sheng Q, Wu XY, Ye BC, Zhang B. Jiang Y, et al. Crit Rev Biotechnol. 2021 Mar;41(2):172-185. doi: 10.1080/07388551.2020.1844625. Epub 2020 Nov 5. Crit Rev Biotechnol. 2021. PMID: 33153325 Review.
As an important semi-essential amino acid, l-arginine is extensively used in the food and pharmaceutical fields. At present, l-arginine production depends on cost-effective, green, and sustainable microbial fermentation by using a renewable carbon sour …
As an important semi-essential amino acid, l-arginine is extensively used in the food and pharmaceutical fields. At present, …
The Effectiveness of L-arginine in Clinical Conditions Associated with Hypoxia.
Kurhaluk N. Kurhaluk N. Int J Mol Sci. 2023 May 3;24(9):8205. doi: 10.3390/ijms24098205. Int J Mol Sci. 2023. PMID: 37175912 Free PMC article. Review.
The review summarises the data of the last 50 years on the effectiveness of the amino acid L-arginine in therapeutic practice in conditions accompanied by different-origin hypoxia. ...The review presents a generalised analysis of techniques, data on L-argi …
The review summarises the data of the last 50 years on the effectiveness of the amino acid L-arginine in therapeutic practice …
L-arginine effect on inflammatory mediators: A systematic review of randomized controlled clinical trials.
Mirhafez SR, Hariri M. Mirhafez SR, et al. Int J Vitam Nutr Res. 2021 Sep;91(5-6):562-570. doi: 10.1024/0300-9831/a000619. Epub 2019 Nov 11. Int J Vitam Nutr Res. 2021. PMID: 31699008 Free article.
L-arginine is an important factor in several physiological and biochemical processes. ...Our results indicated that L-arginine might not be able to reduce selected inflammatory mediators, but for making a firm decision more studies are needed to be con …
L-arginine is an important factor in several physiological and biochemical processes. ...Our results indicated that L- …
The Role of L-Arginine-NO System in Female Reproduction: A Narrative Review.
Bodis J, Farkas B, Nagy B, Kovacs K, Sulyok E. Bodis J, et al. Int J Mol Sci. 2022 Nov 28;23(23):14908. doi: 10.3390/ijms232314908. Int J Mol Sci. 2022. PMID: 36499238 Free PMC article. Review.
Accumulating evidence are available on the involvement of l-arginine-nitric oxide (NO) system in complex biological processes and numerous clinical conditions. Particular attention was made to reveal the association of l-arginine and methylarginines to …
Accumulating evidence are available on the involvement of l-arginine-nitric oxide (NO) system in complex biological processes …
[L-arginine].
Higashi Y, Matsuura H, Kajiyama G. Higashi Y, et al. Nihon Rinsho. 2000 Jan;58 Suppl 1:184-7. Nihon Rinsho. 2000. PMID: 11026261 Review. Japanese. No abstract available.
L-Arginine in Cancer Immunity and Therapy.
Xiao Y, Jin M, Zong Y, Chen Y, Wu M, Liu H. Xiao Y, et al. Mol Nutr Food Res. 2026 Mar;70(6):e70446. doi: 10.1002/mnfr.70446. Mol Nutr Food Res. 2026. PMID: 41860423 Review.
L-Arginine (L-Arg), a conditionally essential and versatile amino acid, exhibits important research values in cancer biology and therapy. ...However, intrinsic heterogeneity across tumor types has yielded seemingly contradictory findings-elimination of L-Arg …
L-Arginine (L-Arg), a conditionally essential and versatile amino acid, exhibits important research values in cancer bi …
152,067 results
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