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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1910 1
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1924 1
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1928 4
1929 1
1930 3
1931 3
1932 5
1933 6
1934 3
1935 2
1936 3
1937 3
1938 2
1939 2
1940 1
1941 8
1942 3
1943 1
1944 2
1945 17
1946 43
1947 48
1948 46
1949 30
1950 64
1951 72
1952 78
1953 89
1954 88
1955 88
1956 110
1957 81
1958 87
1959 63
1960 100
1961 89
1962 126
1963 249
1964 436
1965 344
1966 386
1967 444
1968 571
1969 537
1970 632
1971 705
1972 620
1973 614
1974 611
1975 681
1976 621
1977 622
1978 561
1979 568
1980 636
1981 683
1982 739
1983 860
1984 1007
1985 1066
1986 1154
1987 1229
1988 1418
1989 1609
1990 1800
1991 2033
1992 2211
1993 2284
1994 2622
1995 2856
1996 3316
1997 3639
1998 3915
1999 3933
2000 4454
2001 4491
2002 4658
2003 4913
2004 4871
2005 4634
2006 4969
2007 5055
2008 5067
2009 5062
2010 5209
2011 5607
2012 5642
2013 5689
2014 5503
2015 5445
2016 5278
2017 5516
2018 5434
2019 5492
2020 5731
2021 5685
2022 5285
2023 4907
2024 5045
2025 5288
2026 794

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Page 1
Transition of Conformation and Solubility in beta-Sheet-Structured Poly(l-cysteine)s with Methylthio or Sulfonium Pendants.
Zhu S, Xue R, Yu Z, Zhang X, Luan S, Tang H. Zhu S, et al. Biomacromolecules. 2021 Mar 8;22(3):1211-1219. doi: 10.1021/acs.biomac.0c01715. Epub 2021 Feb 3. Biomacromolecules. 2021. PMID: 33533606
Poly(l-cysteine)s with methylthio pendants (PMTLCs) were synthesized by ring-opening polymerization of a new l-cysteine-based N-carboxyanhydride. ...
Poly(l-cysteine)s with methylthio pendants (PMTLCs) were synthesized by ring-opening polymerization of a new l- …
L-cysteine protective effects against platelet disaggregation and echinocyte occurrence in gentamicin-induced kidney injury.
Suljević D, Mitrašinović-Brulić M, Fočak M. Suljević D, et al. Mol Cell Biochem. 2023 Jan;478(1):13-22. doi: 10.1007/s11010-022-04498-x. Epub 2022 Jun 16. Mol Cell Biochem. 2023. PMID: 35708867
Morphological alteration of blood cells, leukocytes and platelets count, as well as biochemical effects of L-cysteine (Cys) and antibiotic gentamicin, in clinically healthy male Wistar rats, were studied. ...L-cysteine and 80 mg/kg b.w. gentamicin i.p. …
Morphological alteration of blood cells, leukocytes and platelets count, as well as biochemical effects of L-cysteine (Cys) an …
The metabolism of S-methyl-L-cysteine.
Sklan NM, Barnsley EA. Sklan NM, et al. Biochem J. 1968 Mar;107(2):217-23. doi: 10.1042/bj1070217. Biochem J. 1968. PMID: 5641877 Free PMC article.
Methylsulphinylacetic acid, 2-hydroxy-3-methylsulphinylpropionic acid and methylmercapturic acid sulphoxide (N-acetyl-S-methyl-l-cysteine S-oxide) were isolated as their dicyclohexylammonium salts from the urine of rats after they had been dosed with S-methyl …
Methylsulphinylacetic acid, 2-hydroxy-3-methylsulphinylpropionic acid and methylmercapturic acid sulphoxide (N-acetyl-S-methyl-l-c …
The mercapturic acid pathway.
Hanna PE, Anders MW. Hanna PE, et al. Crit Rev Toxicol. 2019 Nov;49(10):819-929. doi: 10.1080/10408444.2019.1692191. Epub 2020 Jan 16. Crit Rev Toxicol. 2019. PMID: 31944156 Free article.
Although mercapturic acid formation and elimination is a detoxication reaction, l-cysteine S-conjugates may undergo bioactivation by cysteine S-conjugate beta-lyase. Moreover, some l-cysteine S-conjugates, particularly l-cys …
Although mercapturic acid formation and elimination is a detoxication reaction, l-cysteine S-conjugates may undergo bio …
L-Cysteine and L-AP4 microinjections in the rat caudal ventrolateral medulla decrease arterial blood pressure.
Takemoto Y. Takemoto Y. Auton Neurosci. 2014 Dec;186:45-53. doi: 10.1016/j.autneu.2014.09.018. Epub 2014 Oct 2. Auton Neurosci. 2014. PMID: 25450419
Central L-cysteine's action could be independent of the L-AP4 sensitive receptors. Cardiovascular regulation may involve endogenous L-cysteine in the CVLM. Further multidisciplinary examinations are required to elaborate on L-cysteine …
Central L-cysteine's action could be independent of the L-AP4 sensitive receptors. Cardiovascular regulation may involv …
N-acetyl-L-cysteine improves the performance of chronic cyclic heat-stressed finisher broilers but has no effect on tissue glutathione levels.
Pertiwi H, Majdeddin M, Degroote J, Zhang H, Michiels J. Pertiwi H, et al. Br Poult Sci. 2023 Dec;64(6):751-762. doi: 10.1080/00071668.2023.2264234. Epub 2023 Dec 18. Br Poult Sci. 2023. PMID: 37782109 Free article.
It was hypothesised that dietary N-acetyl-L-cysteine (NAC) in feed, as a source of cysteine, could improve the performance of heat-stressed finisher broilers by fostering glutathione (GSH) synthesis. ...However, this was not associated with changes in tissue …
It was hypothesised that dietary N-acetyl-L-cysteine (NAC) in feed, as a source of cysteine, could improve the performa …
Identification of tryptophanase from Escherichia coli for the synthesis of S-allyl-l-cysteine and related S-substituted cysteine derivatives.
Mizutani T, Hara R, Iihoshi T, Kozono S, Takeuchi M, Hibi M, Takahashi S, Ueda M, Ogawa J. Mizutani T, et al. J Biosci Bioeng. 2022 Sep;134(3):182-186. doi: 10.1016/j.jbiosc.2022.06.001. Epub 2022 Jun 25. J Biosci Bioeng. 2022. PMID: 35764447
A wide variety of S-substituted cysteine derivatives occur in plant metabolites. For example, S-allyl-l-cysteine (SAC), mainly contained in garlic, gathers huge interest because of its favorable bioactivities for human health. ...Our results showed a novel su …
A wide variety of S-substituted cysteine derivatives occur in plant metabolites. For example, S-allyl-l-cysteine (SAC), …
S-carboxymethyl-L-cysteine and it (R/S)-S-oxides in beagle dog plasma and hepatic cytosol.
Panagopoulos P, Mitchell SC, Steventon GB. Panagopoulos P, et al. Xenobiotica. 2015;45(12):1047-53. doi: 10.3109/00498254.2015.1042538. Epub 2015 Jun 11. Xenobiotica. 2015. PMID: 26068525
Incubation of beagle hepatic cytosol, under conditions promoting phenylalanine hydroxylase activity, led to the formation of the sulfoxide derivatives of S-carboxymethyl-L-cysteine, N-acetyl-S-carboxymethyl-L-cysteine, S-methyl-L-cyste …
Incubation of beagle hepatic cytosol, under conditions promoting phenylalanine hydroxylase activity, led to the formation of the sulfoxide d …
Oral Administration of (S)-Allyl-l-Cysteine and Aged Garlic Extract to Rats: Determination of Metabolites and Their Pharmacokinetics.
Park T, Oh JH, Lee JH, Park SC, Jang YP, Lee YJ. Park T, et al. Planta Med. 2017 Nov;83(17):1351-1360. doi: 10.1055/s-0043-111895. Epub 2017 May 30. Planta Med. 2017. PMID: 28561204
(S)-Allyl-l-cysteine is the major bioactive compound in garlic. (S)-Allyl-l-cysteine is metabolized to (S)-allyl-l-cysteine sulfoxide, N-acetyl-(S)-allyl-l-cysteine, and N-acetyl-(S)-allyl-l-cysteine sulfoxide …
(S)-Allyl-l-cysteine is the major bioactive compound in garlic. (S)-Allyl-l-cysteine is metabolized to (S)-allyl …
Synthesis of L-cysteine derivatives of immunotropic activity.
Kwapiszewski W, Iliaszenko J, Sokołowska-Muszyńska M. Kwapiszewski W, et al. Arch Immunol Ther Exp (Warsz). 1981;29(6):823-6. Arch Immunol Ther Exp (Warsz). 1981. PMID: 7349103
In continued search for new compounds with immunotropic and anti-inflammatory activity we developed synthesis of the seven following new derivatives of L-cysteine: S-methyl-N-acetylcysteine amide, hydrazide and acetylhydrazide, acetyl derivatives of S-methyl- …
In continued search for new compounds with immunotropic and anti-inflammatory activity we developed synthesis of the seven following new der …
170,624 results
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