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Page 1
Did you mean amino acid transmembrane transporter activity (6,785 results)?
Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.
Torrents D, Estévez R, Pineda M, Fernández E, Lloberas J, Shi YB, Zorzano A, Palacín M. Torrents D, et al. J Biol Chem. 1998 Dec 4;273(49):32437-45. doi: 10.1074/jbc.273.49.32437. J Biol Chem. 1998. PMID: 9829974 Free article.
We have identified a new human cDNA (y+L amino acid transporter-1 (y+LAT-1)) that induces system y+L transport activity with 4F2hc (the surface antigen 4F2 heavy chain) in oocytes. ...Mutation of the human 4F2hc residue cysteine 109 (Cys- …
We have identified a new human cDNA (y+L amino acid transporter-1 (y+LAT-1)) that induces system y+L transpor …
The amino acid transport system y+L/4F2hc is a heteromultimeric complex.
Estévez R, Camps M, Rojas AM, Testar X, Devés R, Hediger MA, Zorzano A, Palacín M. Estévez R, et al. FASEB J. 1998 Oct;12(13):1319-29. doi: 10.1096/fasebj.12.13.1319. FASEB J. 1998. PMID: 9761775
We show that expression of system y+L-like amino acid transport activity by 4F2hc in oocytes is limited by an endogenous factor and that direct covalent modification of external cysteine residue(s) of an oocyte membrane protein blocks system y+L/4F2hc …
We show that expression of system y+L-like amino acid transport activity by 4F2hc in oocytes is limited by an endogenou …
Role of transmembrane domain 8 in substrate selectivity and translocation of SteT, a member of the L-amino acid transporter (LAT) family.
Bartoccioni P, Del Rio C, Ratera M, Kowalczyk L, Baldwin JM, Zorzano A, Quick M, Baldwin SA, Vázquez-Ibar JL, Palacín M. Bartoccioni P, et al. J Biol Chem. 2010 Sep 10;285(37):28764-76. doi: 10.1074/jbc.M110.116632. Epub 2010 Jul 7. J Biol Chem. 2010. PMID: 20610400 Free PMC article.
System l-amino acid transporters (LAT) belong to the amino acid, polyamine, and organic cation superfamily of transporters and include the light subunits of heteromeric amino acid transporters and prokaryotic homologues. ... …
System l-amino acid transporters (LAT) belong to the amino acid, polyamine, and organic cation superfamil …
Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity.
Yao SY, Muzyka WR, Elliott JF, Cheeseman CI, Young JD. Yao SY, et al. Biochem J. 1998 Mar 1;330 ( Pt 2)(Pt 2):745-52. doi: 10.1042/bj3300745. Biochem J. 1998. PMID: 9480885 Free PMC article.
Two different protein families, designated CAT (cationic amino acid transporter) and BAT (broad-specificity amino acid transporter) mediate the plasma membrane transport of cationic amino acids in animal cells. ...These characteris …
Two different protein families, designated CAT (cationic amino acid transporter) and BAT (broad-specificity amino acid …
Erythrocytic metabolism of ATLX-0199: An agent that increases minute ventilation.
Krasinkiewicz JM, Hubbard D, Perez de Guzman N, Masters A, Zhao Y, Gaston H, Gaston B. Krasinkiewicz JM, et al. Biochem Biophys Res Commun. 2023 Nov 5;680:171-176. doi: 10.1016/j.bbrc.2023.09.030. Epub 2023 Sep 15. Biochem Biophys Res Commun. 2023. PMID: 37741264 Free PMC article.
CSNO binding inhibits these channels in the carotid body, leading to increased minute ventilation in vivo. However, only the l-isomer is active in vivo because it requires the l-amino acid transporter (LAT) for transmembrane transport …
CSNO binding inhibits these channels in the carotid body, leading to increased minute ventilation in vivo. However, only the l-isomer is …
LncRNA SLC1A5-AS/MZF1/ASCT2 Axis Contributes to Malignant Progression of Hepatocellular Carcinoma.
Jiang J, Dong W, Zhang W, Wang Q, Wang R, Wang J, Wu H, Dong H, Zhao RC, Wang J, Li Z. Jiang J, et al. Discov Med. 2023 Dec;35(179):995-1014. doi: 10.24976/Discov.Med.202335179.96. Discov Med. 2023. PMID: 38058065 Free article.
Luciferase reporter assays and chromatin immunoprecipitation (ChIP) were utilized to authenticate the effects of the predicted transcription factors on SLC1A5 promoter activity. RESULTS: Following the screening, we identified CTB-147N14.6, derived from the antisense strand …
Luciferase reporter assays and chromatin immunoprecipitation (ChIP) were utilized to authenticate the effects of the predicted transcription …
Knockout of latrophilin-3 in Sprague-Dawley rats causes hyperactivity, hyper-reactivity, under-response to amphetamine, and disrupted dopamine markers.
Regan SL, Hufgard JR, Pitzer EM, Sugimoto C, Hu YC, Williams MT, Vorhees CV. Regan SL, et al. Neurobiol Dis. 2019 Oct;130:104494. doi: 10.1016/j.nbd.2019.104494. Epub 2019 Jun 6. Neurobiol Dis. 2019. PMID: 31176715 Free PMC article.
We tested WT and KO littermates for home-cage activity, anxiety-like behavior, acoustic startle response, and activity after amphetamine challenge. ...Expression of Lphn1, Lphn2, and Flrt3 by qPCR and their protein products by western-blot analysis showed no compens …
We tested WT and KO littermates for home-cage activity, anxiety-like behavior, acoustic startle response, and activity after a …
Functional characterization of two S-nitroso-L-cysteine transporters, which mediate movement of NO equivalents into vascular cells.
Li S, Whorton AR. Li S, et al. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1263-71. doi: 10.1152/ajpcell.00382.2006. Epub 2006 Nov 8. Am J Physiol Cell Physiol. 2007. PMID: 17092994 Free article.
System L amino acid transporters have been shown to be responsible for cellular uptake of S-nitroso-L-cysteine (l-CSNO). ...Transport of L-CSNO into red blood cells, endothelial cells, and smooth muscle cells was inhibited by 2-aminobicyclo(2.2. …
System L amino acid transporters have been shown to be responsible for cellular uptake of S-nitroso-L-cysteine ( …
The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers.
Papo N, Oren Z, Pag U, Sahl HG, Shai Y. Papo N, et al. J Biol Chem. 2002 Sep 13;277(37):33913-21. doi: 10.1074/jbc.M204928200. Epub 2002 Jul 10. J Biol Chem. 2002. PMID: 12110678 Free article.
Most of the studies were carried out with l-amino acid peptides possessing amphipathic alpha-helix or beta-sheet structures, which are known to be important for biological activities. ...Interestingly, the effect of sequence alteration on bio …
Most of the studies were carried out with l-amino acid peptides possessing amphipathic alpha-helix or beta-sheet struct …
Spectroscopic studies of the interaction of Ca2+-ATPase-peptides with dodecyl maltoside and its brominated analog.
Soulié S, de Foresta B, Møller JV, Bloomberg GB, Groves JD, le Maire M. Soulié S, et al. Eur J Biochem. 1998 Oct 1;257(1):216-27. doi: 10.1046/j.1432-1327.1998.2570216.x. Eur J Biochem. 1998. PMID: 9799122 Free article.
We report here the structure and properties of three synthetic peptides with a single Trp representing the M6 and M7 regions implicated in Ca2+ binding: peptide M6 (amino acid residues 785-810), peptide M7-L (amino acid residues 808-847) corresponding …
We report here the structure and properties of three synthetic peptides with a single Trp representing the M6 and M7 regions implicated in C …
15 results