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1996 1
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2,155 results

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Page 1
LL-37 transports immunoreactive cGAMP to activate STING signaling and enhance interferon-mediated host antiviral immunity.
Wei X, Zhang L, Yang Y, Hou Y, Xu Y, Wang Z, Su H, Han F, Han J, Liu P, Hu S, Koci MD, Sun X, Zhang C. Wei X, et al. Cell Rep. 2022 May 31;39(9):110880. doi: 10.1016/j.celrep.2022.110880. Cell Rep. 2022. PMID: 35649354 Free article.
LL-37 specifically binds cGAMP and efficiently delivers cGAMP into target cells. cGAMP transferred by LL-37 activates robust interferon responses and host antiviral immunity in a STING-dependent manner. Furthermore, we report that LL-37 i
LL-37 specifically binds cGAMP and efficiently delivers cGAMP into target cells. cGAMP transferred by LL-37 acti
Therapeutic Potential of Cathelicidin Peptide LL-37, an Antimicrobial Agent, in a Murine Sepsis Model.
Nagaoka I, Tamura H, Reich J. Nagaoka I, et al. Int J Mol Sci. 2020 Aug 19;21(17):5973. doi: 10.3390/ijms21175973. Int J Mol Sci. 2020. PMID: 32825174 Free PMC article. Review.
In different species of mammals, the cathelicidin family of antimicrobial peptides AMPs has been identified, and in humans, LL-37 is the only type of cathelicidin identified. LL-37 has many different biological activities, such as regulation of respons …
In different species of mammals, the cathelicidin family of antimicrobial peptides AMPs has been identified, and in humans, LL-37
Regulation of LL-37 in Bone and Periodontium Regeneration.
Chinipardaz Z, Zhong JM, Yang S. Chinipardaz Z, et al. Life (Basel). 2022 Sep 30;12(10):1533. doi: 10.3390/life12101533. Life (Basel). 2022. PMID: 36294968 Free PMC article. Review.
LL-37 also manifests other functions such as promoting wound healing, angiogenesis, cell differentiation, and modulating apoptosis. This review summarizes the current studies on the structure, expression, and function of LL-37 and highlights the contri
LL-37 also manifests other functions such as promoting wound healing, angiogenesis, cell differentiation, and modulating apopt
Antibiofilm properties of cathelicidin LL-37: an in-depth review.
Memariani H, Memariani M. Memariani H, et al. World J Microbiol Biotechnol. 2023 Feb 14;39(4):99. doi: 10.1007/s11274-023-03545-z. World J Microbiol Biotechnol. 2023. PMID: 36781570 Review.
Endogenous host defense peptides, such as the human cathelicidin LL-37, are being propounded as promising options for treating such infectious diseases. ...Undoubtedly, LL-37 can open up new windows of opportunity to prevent and treat obstinate biofilm …
Endogenous host defense peptides, such as the human cathelicidin LL-37, are being propounded as promising options for treating …
Cathelicidin LL-37: A new important molecule in the pathophysiology of systemic lupus erythematosus.
Moreno-Angarita A, Aragón CC, Tobón GJ. Moreno-Angarita A, et al. J Transl Autoimmun. 2019 Dec 17;3:100029. doi: 10.1016/j.jtauto.2019.100029. eCollection 2020. J Transl Autoimmun. 2019. PMID: 32743514 Free PMC article. Review.
In this article, we reviewed the structure, function, and importance of LL-37 in innate immunity, as well as its biological plausibility in the pathophysiology of autoimmune diseases such as SLE. In this narrative review, we included primary journal articles describ …
In this article, we reviewed the structure, function, and importance of LL-37 in innate immunity, as well as its biological pl …
Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model.
Zhang H, Yuan X, Yang Y, Wanyan Y, Tao L, Chen Y. Zhang H, et al. Cell Adh Migr. 2023 Dec;17(1):20-34. doi: 10.1080/19336918.2023.2168231. Cell Adh Migr. 2023. PMID: 36656313 Free PMC article.
The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis remains unclear. Here, we confirmed that LL-37 expression enhanced endothelial-mesenchymal transition (EMT), migration and invasion in HCC cells. ...
The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis remains unclear. Here, we confirmed that …
The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent.
Ridyard KE, Overhage J. Ridyard KE, et al. Antibiotics (Basel). 2021 May 29;10(6):650. doi: 10.3390/antibiotics10060650. Antibiotics (Basel). 2021. PMID: 34072318 Free PMC article. Review.
While LL-37 has shown promising results, it has yet to receive regulatory approval as a peptide antibiotic. ...The possible methods to overcome these challenges, including immobilization techniques, LL-37 delivery systems, the development of LL- …
While LL-37 has shown promising results, it has yet to receive regulatory approval as a peptide antibiotic. ...The possible me …
LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity.
Fabisiak A, Murawska N, Fichna J. Fabisiak A, et al. Pharmacol Rep. 2016 Aug;68(4):802-8. doi: 10.1016/j.pharep.2016.03.015. Epub 2016 Apr 7. Pharmacol Rep. 2016. PMID: 27117377 Review.
They are designed to prevent pathogens from colonization. Among them, defensins and cathelicidins could be found. LL-37, the sole human cathelicidin draws particular attention because of its outstanding abilities. In addition to being a broad spectrum antibiotic, …
They are designed to prevent pathogens from colonization. Among them, defensins and cathelicidins could be found. LL-37, the s …
Antifungal properties of cathelicidin LL-37: current knowledge and future research directions.
Memariani M, Memariani H. Memariani M, et al. World J Microbiol Biotechnol. 2023 Dec 7;40(1):34. doi: 10.1007/s11274-023-03852-5. World J Microbiol Biotechnol. 2023. PMID: 38057654 Review.
Recent years have witnessed an explosion in knowledge on microbicidal activity of LL-37, the sole human cathelicidin. Herein, we provide a summary of the current understanding about antifungal properties of LL-37, with particular emphasis on its molecu …
Recent years have witnessed an explosion in knowledge on microbicidal activity of LL-37, the sole human cathelicidin. Herein, …
Structural Plasticity of LL-37 Indicates Elaborate Functional Adaptation Mechanisms to Bacterial Target Structures.
Zeth K, Sancho-Vaello E. Zeth K, et al. Int J Mol Sci. 2021 May 14;22(10):5200. doi: 10.3390/ijms22105200. Int J Mol Sci. 2021. PMID: 34068993 Free PMC article. Review.
The human cathelicidin LL-37 is a multifunctional peptide of the human innate immune system. Among the various functions of LL-37, its antimicrobial activity is important in controlling the microorganisms of the human body. ...
The human cathelicidin LL-37 is a multifunctional peptide of the human innate immune system. Among the various functions of …
2,155 results