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The nuts and bolts of low-level laser (light) therapy.
Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. Chung H, et al. Ann Biomed Eng. 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7. Epub 2011 Nov 2. Ann Biomed Eng. 2012. PMID: 22045511 Free PMC article. Review.
In recent years the field sometimes known as photobiomodulation has broadened to include light-emitting diodes and other light sources, and the range of wavelengths used now includes many in the red and near infrared. The term "low level laser …
In recent years the field sometimes known as photobiomodulation has broadened to include light-emitting diodes and other li
Mechanisms and applications of the anti-inflammatory effects of photobiomodulation.
Hamblin MR. Hamblin MR. AIMS Biophys. 2017;4(3):337-361. doi: 10.3934/biophy.2017.3.337. Epub 2017 May 19. AIMS Biophys. 2017. PMID: 28748217 Free PMC article.
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. ...Tertiary effects include activation of a wide range of transcription f
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared ligh
Biphasic dose response in low level light therapy - an update.
Huang YY, Sharma SK, Carroll J, Hamblin MR. Huang YY, et al. Dose Response. 2011;9(4):602-18. doi: 10.2203/dose-response.11-009.Hamblin. Epub 2011 Sep 2. Dose Response. 2011. PMID: 22461763 Free PMC article.
Low-level laser (light) therapy (LLLT) has been known since 1967 but still remains controversial due to incomplete understanding of the basic mechanisms and the selection of inappropriate dosimetric parameters that led to negative studies. The
Low-level laser (light) therapy (LLLT) has been known since 1967 but still remains controversial due to i
Biphasic Dose/Response of Photobiomodulation Therapy on Culture of Human Fibroblasts.
Flores Luna GL, de Andrade ALM, Brassolatti P, Bossini PS, Anibal FF, Parizotto NA, Leal ÂMO. Flores Luna GL, et al. Photobiomodul Photomed Laser Surg. 2020 Jul;38(7):413-418. doi: 10.1089/photob.2019.4729. Epub 2020 Mar 24. Photobiomodul Photomed Laser Surg. 2020. PMID: 32208063
Methods: The cell used as a template for cell proliferation was HFF-1. For the photobiomodulation (PBM) application, a 660 nm laser with a power of 40 mW and energies of 0.84, 1.40, 5.88, and 6.72 J was used. ...
Methods: The cell used as a template for cell proliferation was HFF-1. For the photobiomodulation (PBM) application, a 660 nm laser w …
Biphasic dose response in the anti-inflammation experiment of PBM.
Nie F, Hao S, Ji Y, Zhang Y, Sun H, Will M, Han W, Ding Y. Nie F, et al. Lasers Med Sci. 2023 Feb 7;38(1):66. doi: 10.1007/s10103-022-03664-3. Lasers Med Sci. 2023. PMID: 36749428 Review.
Non-invasive laser irradiation can induce photobiomodulation (PBM) effects in cells and tissues, which can help reduce inflammation and pain in several clinical scenarios. ...A better understanding of the extent of dualistic dose response in low-intensity laser t
Non-invasive laser irradiation can induce photobiomodulation (PBM) effects in cells and tissues, which can help reduce inflammation a …
The hormetic dose-response mechanism: Nrf2 activation.
Calabrese EJ, Kozumbo WJ. Calabrese EJ, et al. Pharmacol Res. 2021 May;167:105526. doi: 10.1016/j.phrs.2021.105526. Epub 2021 Mar 2. Pharmacol Res. 2021. PMID: 33667690 Review.
Nrf2 can be activated by numerous oxidative stressors (e.g., exercise, caloric restriction/intermittent fasting) and by exposures to synthetic, naturally occurring and endogenous chemicals, to non-ionizing (e.g., low-level light) and ionizing radiation, and t …
Nrf2 can be activated by numerous oxidative stressors (e.g., exercise, caloric restriction/intermittent fasting) and by exposures to synthet …
Exploring the biphasic dose-response effects of photobiomodulation on the viability, migration, and extracellular vesicle secretion of human adipose mesenchymal stem cells.
Chang CY, Aviña AE, Chang CJ, Lu LS, Chong YY, Ho TY, Yang TS. Chang CY, et al. J Photochem Photobiol B. 2024 Jul;256:112940. doi: 10.1016/j.jphotobiol.2024.112940. Epub 2024 May 14. J Photochem Photobiol B. 2024. PMID: 38776590
Photobiomodulation (PBM) is a well-established medical technology that employs diverse light sources like lasers or light-emitting diodes to generate diverse photochemical and photophysical reactions in cells, thereby producing beneficial clinical outcomes. I
Photobiomodulation (PBM) is a well-established medical technology that employs diverse light sources like lasers or light
Biphasic dose-response and effects of near-infrared photobiomodulation on erythrocytes susceptibility to oxidative stress in vitro.
Walski T, Grzeszczuk-Kuć K, Mehl J, Bohara R, Trochanowska-Pauk N, Detyna J, Komorowska M. Walski T, et al. J Photochem Photobiol B. 2024 Aug;257:112958. doi: 10.1016/j.jphotobiol.2024.112958. Epub 2024 Jun 11. J Photochem Photobiol B. 2024. PMID: 38875890 Free article.
Continuous NIR exposure revealed a biphasic response in cell-free hemoglobin changes, with antioxidative effects observed at low fluences and detrimental effects at higher fluences. ...Protective effects were also tested across wavelengths in the range of 750-1100 nm, with …
Continuous NIR exposure revealed a biphasic response in cell-free hemoglobin changes, with antioxidative effects observed at low flue …
Near-Infrared Light and Skin: Why Intensity Matters.
Barolet D. Barolet D. Curr Probl Dermatol. 2021;55:374-384. doi: 10.1159/000517645. Epub 2021 Oct 25. Curr Probl Dermatol. 2021. PMID: 34698043 Review.
Infrared light (760 nm-1 mm) constitutes approximately 40% of the solar radiation reaching the ground at sea level. ...In fact, the biphasic dose curve (Arndt-Schulz curve) of photobiomodulation establishes that if irradiance is lower than the physiolo …
Infrared light (760 nm-1 mm) constitutes approximately 40% of the solar radiation reaching the ground at sea level. ...In fact, the …
Effect of Photobiomodulation Therapy Associated With Biphasic Phosphate Calcium on Bone Repair: A Histomorphometric Study in Rats.
De Marco AC, Cavassini Torquato L, Camacho Ribeiro T, Moretto Nunes C, Vicensotto Bernardo A, Martins Maciel CC, Alberto Pereira K, Neves Jardini MA, Pedrine Santamaria M. De Marco AC, et al. J Lasers Med Sci. 2022 Aug 15;13:e33. doi: 10.34172/jlms.2022.33. eCollection 2022. J Lasers Med Sci. 2022. PMID: 36743134 Free PMC article.
Introduction: This study aimed to investigate the effects of photobiomodulation (PBM) therapy associated with biphasic calcium phosphate on calvaria critical defects in rats. ...A low-level a gallium aluminum arsenide (GaAlAs) laser was applied …
Introduction: This study aimed to investigate the effects of photobiomodulation (PBM) therapy associated with biphasic
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