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The nuts and bolts of low-level laser (light) therapy.
Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. Chung H, et al. Ann Biomed Eng. 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7. Epub 2011 Nov 2. Ann Biomed Eng. 2012. PMID: 22045511 Free PMC article. Review.
The term "low level laser therapy" or LLLT has become widely recognized and implies the existence of the biphasic dose response or the Arndt-Schulz curve. This review will cover the mechanisms of action of LLLT at a cellular and at …
The term "low level laser therapy" or LLLT has become widely recognized and implies the existence of the biph …
Mechanisms and applications of the anti-inflammatory effects of photobiomodulation.
Hamblin MR. Hamblin MR. AIMS Biophys. 2017;4(3):337-361. doi: 10.3934/biophy.2017.3.337. Epub 2017 May 19. AIMS Biophys. 2017. PMID: 28748217 Free PMC article.
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. ...There is a pronounced biphasic dose response wher …
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared …
Evaluation of the Effects of Low-Level Laser Therapy on Diabetic Bone Healing.
Diker N, Aytac D, Helvacioglu F, Dagdelen C, Oguz Y. Diker N, et al. J Craniofac Surg. 2019 Oct;30(7):1994-1998. doi: 10.1097/SCS.0000000000005654. J Craniofac Surg. 2019. PMID: 31232987
The aim of the present study was to evaluate the effects of low-level laser therapy (LLLT) and biphasic alloplastic bone graft material on diabetic bone healing. ...Right defects were filled with biphasic alloplastic bone graft. Rats were …
The aim of the present study was to evaluate the effects of low-level laser therapy (LLLT) and biphasic a …
Biphasic Dose/Response of Photobiomodulation Therapy on Culture of Human Fibroblasts.
Flores Luna GL, de Andrade ALM, Brassolatti P, Bossini PS, Anibal FF, Parizotto NA, Leal ÂMO. Flores Luna GL, et al. Photobiomodul Photomed Laser Surg. 2020 Jul;38(7):413-418. doi: 10.1089/photob.2019.4729. Epub 2020 Mar 24. Photobiomodul Photomed Laser Surg. 2020. PMID: 32208063
For the photobiomodulation (PBM) application, a 660 nm laser with a power of 40 mW and energies of 0.84, 1.40, 5.88, and 6.72 J was used. ...
For the photobiomodulation (PBM) application, a 660 nm laser with a power of 40 mW and energies of 0.84, 1.40, 5.88, and 6.72 J was u …
Differential response of human dermal fibroblast subpopulations to visible and near-infrared light: Potential of photobiomodulation for addressing cutaneous conditions.
Mignon C, Uzunbajakava NE, Castellano-Pellicena I, Botchkareva NV, Tobin DJ. Mignon C, et al. Lasers Surg Med. 2018 Oct;50(8):859-882. doi: 10.1002/lsm.22823. Epub 2018 Apr 17. Lasers Surg Med. 2018. PMID: 29665018
Light dose-response at a standard oxygen concentration (20%) at all six wavelengths was evaluated in terms of cell metabolic activity. ...Cell behavior following treatment with 450 nm was biphasic with two distinct states: inhibitory at low- to mid- …
Light dose-response at a standard oxygen concentration (20%) at all six wavelengths was evaluated in terms of cell metabolic a …
An optical system via liquid crystal photonic devices for photobiomodulation.
Chang CM, Lin YH, Srivastava AK, Chigrinov VG. Chang CM, et al. Sci Rep. 2018 Mar 9;8(1):4251. doi: 10.1038/s41598-018-22634-w. Sci Rep. 2018. PMID: 29523829 Free PMC article.
Photobiomodulation or low-level light therapy (LLLT) has extensive applications based on light-induced effects in biological systems. ...The Arndt-Schulz curve states that an optimal dose of light is a key factor for …
Photobiomodulation or low-level light therapy (LLLT) has extensive applications based on light …
Biphasic dose response in low level light therapy - an update.
Huang YY, Sharma SK, Carroll J, Hamblin MR. Huang YY, et al. Dose Response. 2011;9(4):602-18. doi: 10.2203/dose-response.11-009.Hamblin. Epub 2011 Sep 2. Dose Response. 2011. PMID: 22461763 Free PMC article.
Low-level laser (light) therapy (LLLT) has been known since 1967 but still remains controversial due to incomplete understanding of the basic mechanisms and the selection of inappropriate dosimetric parameters that led to negative studies. ...Fu …
Low-level laser (light) therapy (LLLT) has been known since 1967 but still remains controversial due to i …
Biphasic dose response in low level light therapy.
Huang YY, Chen AC, Carroll JD, Hamblin MR. Huang YY, et al. Dose Response. 2009 Sep 1;7(4):358-83. doi: 10.2203/dose-response.09-027.Hamblin. Dose Response. 2009. PMID: 20011653 Free PMC article.
A biphasic dose response has been frequently observed where low levels of light have a much better effect on stimulating and repairing tissues than higher levels of light. The so-called Arndt-Schulz curve is frequently used to describe this b …
A biphasic dose response has been frequently observed where low levels of light have a much better effect on sti …
Repeated transcranial low-level laser therapy for traumatic brain injury in mice: biphasic dose response and long-term treatment outcome.
Xuan W, Huang L, Hamblin MR. Xuan W, et al. J Biophotonics. 2016 Dec;9(11-12):1263-1272. doi: 10.1002/jbio.201500336. Epub 2016 Mar 15. J Biophotonics. 2016. PMID: 26990361 Free PMC article.
This biphasic dose response intrigued us, and we decided to follow the mice that received 3X or 14X laser treatments out to 56-days post-TBI. ...A marker of activated glial cells (GFAP) was significantly increased in the brain regions (compared to both untreated TBI …
This biphasic dose response intrigued us, and we decided to follow the mice that received 3X or 14X laser treatments out to 56 …
Photobiomodulation of human adipose-derived stem cells using 810nm and 980nm lasers operates via different mechanisms of action.
Wang Y, Huang YY, Wang Y, Lyu P, Hamblin MR. Wang Y, et al. Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):441-449. doi: 10.1016/j.bbagen.2016.10.008. Epub 2016 Oct 15. Biochim Biophys Acta Gen Subj. 2017. PMID: 27751953 Free PMC article.
Photobiomodulation (PBM) using red or near-infrared (NIR) light has been used to stimulate the proliferation and differentiation of adipose-derived stem cells. ...Both wavelengths showed a biphasic dose response, but 810nm had a peak dose respon …
Photobiomodulation (PBM) using red or near-infrared (NIR) light has been used to stimulate the proliferation and differentiati …
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